BACKGROUND It is expected that physical dose deposition properties render charged particle dose distributions sensitive to targeting uncertainties. Purpose of this work was to investigate the robustness of scanned-beam particle therapy plans against setup errors for different optimization modalities, beam setups and ion species. MATERIAL AND METHODS For 15 patients with skull base tumors, loc...

PURPOSE The potential of keV cone beam computed tomography (CBCT) for guiding adaptive replanning is well-known. There are impediments to this, one being CBCT number accuracy. The purpose of this study was to investigate CBCT number correction methods and the affect of residual inaccuracies on dose deposition. Four different correction strategies were applied to the same patient data to compare...

introduction accurate estimation of the skin-absorbed dose in external radiation therapy is essential to estimating the probability of secondary carcinogenesis induction materials and methods electron contamination in prostate radiotherapy was investigated using the monte carlo (mc) code calculation. in addition, field size dependence of the skin dose was assessed. excess cancer risk induced by...

Background During radiotherapy of left-sided breast cancer, parts of the heart are irradiated, which may lead to late toxicity. We report on the experience of single institution with cardiac-sparing radiotherapy using voluntary deep inspiration breath hold (V-DIBH) and compare its dosimetric outcome with free breathing (FB) technique. Patients and methods Left-sided breast cancer patients, tr...

Digital Tomosynthesis (DTS) is an image modality in reconstructing tomographic images from two-dimensional kV projections covering a narrow scan angles. Comparing with conventional cone-beam CT (CBCT), it requires less time and radiation dose in data acquisition. It is feasible to apply this technique in patient positioning in radiotherapy. To facilitate its clinical application, a software too...

background and objective: esophageal cancer especially squamous cell carcinoma (scc) is one of the most common gastro intestinal malignancies in north part of iran (khorasan). the standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. several ...

Abstract Background On account of extremity wide range movements and difficulty reproducibility during irradiation sarcomas, assorted immobilization strategies are employed to eliminate setup errors. The study purpose was compare the errors commonly used tools define planning target volume (PTV) margins for each device. Methods A retrospective review comparing Vac-Loc™ thermoplastic cast (Tcast...

background: we evaluated the efficacy of a simple belly-board device (bbd) designed and made in our department for reduction of small bowel inside the post-operative pelvic radiotherapy fields of rectal carcinomas. methods: a very simple bbd was designed and manufactured in our department. it was made of acrylic glass, and was 128 cm long, 40 cm wide, and 9 cm high, with a 25x25 cm square openi...

background and aims. xerostomia is one of the most common complications of head and neck radiotherapy. the aim of this study was to evaluate and compare the efficacy of pilocarpine and bromhexine in improving radiotherapy-induced xerostomia and its associated symptoms. materials and methods. in this single-blind, randomized crossover study, pilocarpine and bromhexine tablets were used by twenty...