Nineteen unanesthetized sheep were given Evans blue dye or radionuclide and then were incrementally bled into hemorrhagic shock (BP less than 50/25) by withdrawal of blood over a period of approximately one hour. Four sheep served as controls for histologic data. Static nuclide brain scans performed in 6 bled sheep demonstrated immediate uptake of the radionuclide. Fluroescence microscopic exa...

Fifty consecutive patients having had cardiac catheterisation for coronary artery disease also underwent testing by three non-invasive methods commonly employed for assessment of left ventricular function. These included the first pass radionuclide ejection fraction, fractional shortening of the M-mode echocardiographic left ventricular internal dimension, and pre-ejection period/left ventricul...

The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular targets. In recent years, different studies ...

Phytoremediation of radioactive waste is a process that uses plants to remove, transfer, or immobilize radionuclides from the contaminated soil, sediment, sludge, or water, and it is a useful method for treating large-scale low-level radionuclide contamination. However, there have not been established criteria which can be utilized to screen out suitable plant species that are capable of remedi...

Practice guidelines from the American Academy of Neurology for the determination of brain death in adults define brain death as "the irreversible loss of function of the brain, including the brainstem." Neurological determination of brain death is primarily based on clinical examination; if clinical criteria are met, a definitive confirmatory test is indicated. The apnea test remains the gold s...

To evaluate cardiac complications associated with electrical injury, 7 patients with high-tension electrical injury (6,600 V alternating current) underwent 201Tl and 123I-metaiodobenzylguanidine (MIBG) imaging in addition to conventional electrocardiographic and echocardiographic assessments. Electrocardiography showed transient atrial fibrillation, second degree atrioventricular block, ST-segm...

Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However, in order to deliver the required dose to the tumor, minimize potential toxicity in normal organs, as well as monitor therapeutic effects, it is important to assess the individualized internal dosimetry based on patient-specific data. Advanced imaging techniques, especially radionuclide imaging, can be used...

A new method utilizing computer subtraction allows 2 separate radionuclide angiograms to be performed during a single laboratory visit. Two separate intravenous injections of the radionuclide are given so that the patient's head can be imaged in 2 different projections. Background activity from the first injection is subtracted by the computer to allow good resolution of blood flow following th...

Two studies were carried out in which 27 and 23 patients respectively with renal space-occupying lesions were assessed by different techniques and the results compared. Instead of proceeding to renal arteriography after the lesion had been found on urography, radionuclide and ultrasound scanning were used in the first study to clarify the nature of the lesions, while in the second study compute...

Breast cancer is the most common non-skin type of cancer and the second leading cause of cancer mortality in women. Advances in diagnosis and treatment have led to declines in mortality, despite an increase in breast cancer incidence. An advancing array of both local and systemic therapy options has led to increasingly individualized treatment. Imaging plays a key role in detecting breast cance...