Magnetically separable gold-nanoparticle catalyst was prepared, and it showed excellent activity for chemoselective reduction of nitroarenes with hydrosilanes.

The recent association of a fatal human case of encephalitis with a newly identified lyssavirus apparently acquired from a native Australian bat has highlighted the possibility that previous human infections have passed urecognised. Infected bats have been identified on the Queensland Gold Coast where extensive close contact between bats and humans has occurred for many years. In an attempt to ...

Diblock copolymer nanoparticles encapsulating a paclitaxel prodrug, Propac 7, have been used to demonstrate the usefulness of a nonmetabolizable radioactive marker, cholesteryl hexadecyl ether (CHE), to evaluate nanoparticle formulation variables. Since CHE did not exchange out of the nanoparticles, the rate of clearance of the CHE could be used as an indicator of nanoparticle stability in vivo...

The functionalisation of therapeutic nanoparticle constructs with cancer-specific biomolecules can enable selective tumour accumulation and targeted treatment. Water soluble gold nanoparticles (ca. 4 nm) stabilised by a mixed monolayer of a hydrophobic zinc phthalocyanine photosensitiser (C11Pc) and hydrophilic polyethylene glycol (PEG) have been prepared. The C11Pc-PEG gold nanoparticle constr...

genetic algorithm and partial least square (ga-pls), the kernel pls (kpls) and levenberg-marquardt artificial neural network (l-m ann) techniques were used to investigate the correlationbetween retention time (rt) and descriptors for 15 nanoparticle compounds which obtained by thecomprehensive two dimensional gas chromatography system (gc x gc). application of thedodecanethiol monolayer-protect...

Magnetoelectrochemical studies of gold nanoparticle quantized capacitance charging were carried out at ambient conditions. The single electron transfer responses were found to be sensitive to external magnetic fields, reflected in the enhancement of voltammetric peak currents and shifts of peak formal potentials with increasing magnetic field intensities. Additionally, splittings of voltammetri...

Radiosensitizers In article 2300305 by Marc-André Fortin and co-workers, the development of a 3D printable gold nanoparticle (AuNP)-containing hydrogel adapted to topical brachytherapy applications is reported. Localized cervical cancer selected as case study. The formulation allows particles be delivered using tailored dosage forms. Once in tumor, AuNPs generate numerous reactive oxygen specie...

Thermally denatured chymotrypsin, lysozyme and papain are substantially refolded towards their native conformation by gold nanoparticle bearing dicarboxylate sidechains.

We have developed an easy method for constructing aptazyme-based logic gates using noncrosslinking gold nanoparticle aggregation.

We present results from nanometer-scale tunnel junctions fabricated using organic self-assembled monolayers ~SAMs! as tunnel barriers. Single junctions have resistances consistent with tunneling through a single layer of molecules. In several devices, a gold nanoparticle nucleated within the SAM barrier. Such samples allow a sensitive test of mechanical stability—some are sufficiently stable to...