The objective of this work is to establish the structural requirements of flavonoids for appreciable radical-scavenging activity (RSA) and elucidate a comprehensive mechanism that can explain their activity. To this end, the RSA of 52 flavonoids against 2,2-diphenyl-1-picrylhydrazyl was determined. The relative change in energy (DeltaH(f)) associated with the formation of various flavonoidal an...

Phytochemicals in plants, vegetables and fruits have been reported to prevent oxidative stress related diseases, such as cancer, cardiovascular disease, cataracts, brain and immune-system dysfunction and inflammation. Many plant phenolic flavonoids have been shown to have antioxidant activity. In our study, the polyphenolic content and the radical scavenging activity of a number of Thai fruit e...

In this study, ethanol extract of Carthamustinctoriuswas studied for superoxide anion scavenging activity. The antioxidant properties of Carthamustinctorius ethanol extract was evaluated using superoxide anion radical scavenging activities. The extract of Carthamustinctorius exhibited strong total antioxidant activity and superoxide anion scavenging activity. This antioxidant activity test were...

INTRODUCTION Jasminum sambac is a sub erect shrub with young shoots of ovate or elliptic glabrous simple leaves, entire margin, and acute apex with opposite arrangement, grown as an ornamental shrub in gardens and cultivated throughout the tropical and subtropical parts of India (1). Leaves, roots and flowers are used as lactifuge. The whole plant is used as diuretic, emmengogue, antihelminthti...

Objective(s):The current study was aimed to determine the bioactive constituents and biological effects of the Crataegus monogyna ethanolic extracts from bark, leaves and berries on hypercholesterolemia. Materials and Methods: Oleanolic acid, ursolic acid, quercetin and lupeol concentrations were quantified by HPLC. Total phenol content and radical scavenging activity of extracts were also mea...

The stem bark of Enantia chlorantha is commonly used for the treatment of malaria and other ailments of the human body such as cough and wound. The plant had been intensely studied for its antimicrobial activities and antipyretic properties. However, the efficacy and mechanisms of action of the plant remain unclear. Therefore, the objective of the present study was to determine the in vitro ant...

Scrophularia umbrosa is a medicinal plant used as a traditional herb. This study was designed to investigate the phytochemical analysis of methanol (MeOH), DCM, and n-Hexane extracts of rhizome as well as total phenol and total flavonoid contents (TPC and TFC). In-vitro β-hematin formation assay and DPPH method were applied for analyzing antimalarial and free-radical scavenging activities of th...

Background and Objectives: Supercritical fluid extraction (SFE) technique has been studied for extraction of bioactive compounds from Feijoa sellowiana leaves. Results were compared with those obtained from conventional ethanolic extraction (CE). Materials and Methods: Results: The best supercritical carbon dioxide (SC-CO2) extraction conditions was determined as 250 bar of pressure, 50 &deg...

The aim of the present study was to evaluate the effect of troxerutin (TXN) on Nickel (Ni) toxicity by using rats and in vitro model. Ni toxicity induced in male albino wistar rats (20 mg/kg body weight (b.w) was administered orally for 20 days). TXN was administered orally (100 mg/kg (b.w) for 20 days with administration of Ni. The toxic effect of Ni and the action of TXN was measure by determ...