Introduction: Breast cancer is one of the most common known cancers in women all around the world. It is the most common cause of death in women after lung cancer. Radiotherapy is a method for therapy of cancer in which certain dose of high energy radiations is used to destruct cancer cells. Radiotherapy is designed so that radiation of eartain does to the target area in body i...

Background: The dosimetric parameters required in lung cancer radiation therapy are taken from a homogeneous water phantom; however, during treatment, the expected results are being affected because of its inhomogeneity. Therefore, it becomes necessary to quantify these deviations.Objective: The present study has been undertaken to find out inter- and intra- lung density variations and its dosi...

PURPOSE Carcinogenesis is an adaptive process between nascent tumor cells and their microenvironment, including the modification of inflammatory responses from antitumorigenic to protumorigenic. Radiation exposure can stimulate inflammatory responses that inhibit or promote carcinogenesis. The purpose of this study is to determine the impact of radiation exposure on lung cancer progression in v...

Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29...

radiotherapy plays an essential role in the management of breast cancer. three-dimensional conformal radiation therapy (3d-crt) is applied based on 3d image information of anatomy of patients. in three-dimensional conformal radiation therapy (3d-crt) for breast cancer one of the common techniques is tangential technique. in this project, various parameters of tangential and supraclavicular fiel...

BACKGROUND Radiation therapy plays an important role in lung carcinoma treatment. However, the incidence of symptomatic radiation-induced lung injury is high. This study aimed to evaluate radioprotective effects of flavonoids extracted from Astragalus complanatus and mechanisms of action against radiation damage. METHODS Alteration in antioxidant status and levles of several cytokines were in...

background: vitamin d, especially its most active metabolite 1,25-dihydroxyvitamin d₃(vit d) is essential in regulating a wide variety of biologic processes, such as regulating mesangial cell activation. the objective of this study was to assess the histopathological changes of effectiveness of vit d as a protective agent against radiation induced lung injury. materials and methods: eighteen wi...

Lung tumors move during breathing depending on patient's breathing conditions, thereby compromising the accurate deposition of radiation doses. It is thus important to calculate the delivered dose to various aspects of the moving tumor and the surrounding normal tissues due to change in tumor shape and location with breathing. In this abstract, we present a computer-based simulation framework t...

Radiation therapy is commonly used for the treatment of lung cancer. However, radiation pneumonitis frequently occurs as a complication of the radiation therapy. Although corticosteroids are widely used for the treatment of radiation pneumonitis, they are not always effective. In this report, we used cyclosporin A in the treatment of a patient suffering from steroid-refractory radiation pneumon...