CASE DESCRIPTION A 74-year-old woman with toxic nodular goiter, diabetes mellitus, depression, gastroesophageal reflux disease, and hypercholesterolemia had routine serum protein electrophoresis done for the first time. Her medications included metformin, levothyroxine, sertraline, rosuvastatin, and rabeprazole. The patient’s renal function was normal. Serum protein electrophoresis was carried ...

We included 90 Hp-infected patients diagnosed histologically. The patients with chronic disease who previously received Hp eradication therapy and underwent gastric surgery were excluded. Patients were randomly divided into 2 groups. The therapy protocol, containing rabeprazole 2x20 mg (Bilim, Kocaeli, Turkey), amoxicillin 2x1 g (Glaxo Smith Kline, İstanbul, Turkey), metronidazole 3x500 mg (I.E...

BACKGROUND There are inconsistent conclusions about whether CYP2C19 variants could affect H. pylori eradication rate in patients treated with the proton pump inhibitor (PPI)-based therapy. We therefore performed a meta-analysis of randomized clinical trials (RCTs) to re-evaluate the impact of CYP2C19 variants on PPI-based triple therapy for the above indication. METHODS All relevant RCTs in t...

To investigate the drug effects of vonoprazan fumarate tablets on reflux esophagitis and their adverse reactions is objective study. A total 102 patients with admitted to Department Gastroenterology Affiliated People’s Hospital Ningbo University from June 2021 November 2022 were selected randomly grouped, 51 cases in observation group control group. The received rabeprazole for 8 w. two groups ...