نتایج جستجو برای: qtc prolongation
تعداد نتایج: 11103 فیلتر نتایج به سال:
BACKGROUND Since the effects of antiemetic doses of droperidol on the QT interval have not been previously studied, the authors designed a randomized, double-blind, placebo-controlled study to evaluate the intraoperative and postoperative effects of small-dose droperidol (0.625 and 1.25 mg intravenous) on the QT interval when used for antiemetic prophylaxis during general anesthesia. METHODS ...
OBJECTIVE To quantify the impact of citalopram and other selective serotonin reuptake inhibitors on corrected QT interval (QTc), a marker of risk for ventricular arrhythmia, in a large and diverse clinical population. DESIGN A cross sectional study using electrocardiographic, prescribing, and clinical data from electronic health records to explore the relation between antidepressant dose and ...
BACKGROUND Levomethadyl acetate, methadone hydrochloride, and buprenorphine hydrochloride are equally effective treatments for opioid dependence. Each blocks the human ether-a-go-go-related gene (hERG)-associated channel in vitro and represents a risk for QT prolongation. To compare the effects of 3 known hERG-associated channel blockers on the corrected QT (QTc), we conducted a randomized, con...
normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background : methadone is a synthetic opioid, used in treatment of chronic pains. the current study was carried out to evaluate the qtc interval in iranian causalities (janbazan) of iran-iraq war receiving maintenance methadone treatment. methods : in 2010, one hundred war causalities in isfahan who chronically take daily dos...
LESSONS LEARNED Cardiotoxicity can be a serious complication of anticancer therapies. To enable earlier identification of drug-related cardiac effects, the International Conference on Harmonization (ICH) adopted the ICH E14 Guidelines for evaluating the potential for QT/corrected QT (QTc) interval prolongation and proarrhythmic potential for nonantiarrhythmic drugs.The results of the evaluation...
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