OBJECTIVE Cerebral injury, in both overt and subtle forms, is common following cardiac surgery. Current methods of assessment, most commonly neuropsychological testing, have several limitations and do not accurately define the anatomical and functional injury that occurs. We have assessed the degree of cerebral injury following on-pump and off-pump cardiac surgery using functional magnetic reso...

Major physiological stress occurs during cardiac surgery with cardiopulmonary bypass. This is related to hypothermia and artificial organ perfusion. Thus, serious gastrointestinal complications, particularly upper gastrointestinal bleeding, sometimes follow cardiac surgery. We have compared the antisecretory effects of a preanesthetic H(2) antagonist (roxatidine, cardiopulmonary bypass-H(2) gro...

Objective: This study aimed to explore the characteristics of perioperative nursing of experimental goats using self-made axial-flow blood pump implantation and provided theoretical nursing knowledge and practice-based evidence for the clinical application of domestically manufactured artificial cardiac pumps. Methods: Seven experimental goats were used in this study, three for pre-testing and ...

BACKGROUND The incidence of strokes has not decreased after coronary artery bypass graft surgery (CABG). The purpose of this study is to identify incidence, risk factors, and temporal pattern of strokes after on-pump and off-pump CABG. METHODS We analyzed 2,516 consecutive patients who underwent first elective isolated CABG. The primary endpoint was strokes within 30 days. The temporal onset ...

BACKGROUND The use of cardiopulmonary bypass during coronary artery bypass surgery (CABG) has been associated with substantial morbidity. The recent introduction of cardiac stabilizers facilitates CABG without cardiopulmonary bypass (off-pump CABG), but it is unknown whether cardiac outcome after off-pump surgery is similar to that for the on-pump procedure. METHODS AND RESULTS In a multicent...

According to the annual registry of the Japanese Association for Coronary Artery Surgery, the percentage of off-pump coronary artery bypass grafting (CABG) procedures performed in Japan in recent years has increased rapidly, comprising of more than 60% of all CABG procedures in 2004. This widespread use of off-pump CABG is mostly owing to the recent technological advances in devices that are sp...

OBJECTIVES The changes in the serum levels of lipopolysaccharide binding protein (LBP) and sCD14 during cardiac surgery were followed in this study. DESIGN Thirty-four patients, 17 in each group, were randomly assigned to coronary artery bypass grafting surgery performed either with ("on-pump") or without ("off-pump") cardiopulmonary bypass. LBP and sCD14 were evaluated by ELISA. RESULTS Th...