BACKGROUND To improve local control rate in patients with breast cancer receiving adjuvant radiotherapy after breast conservative surgery, additional boost dose to the tumor bed could be delivered simultaneously via the simultaneous integrated boost (SIB) modulated technique. However, the position of tumor bed kept changing during the treatment course as the treatment position was aligned to bo...

Offline adaptive radiotherapy (ART) has been used to effectively correct and compensate for prostate motion and reduce the required margin. The efficacy depends on the characteristics of the patient setup error and interfraction motion through the whole treatment; specifically, systematic errors are corrected and random errors are compensated for through the margins. In online image-guided radi...

Background and purpose: There are several alternatives to the widespread ITV strategy in order account for breathing-induced motion PTV margins. The most sophisticated one includes generation of a motion-compensated CT scan with CTV placed its average position – mid-position approach (MidP). In such configuration, margins integrate breathing as another random error. Despite overall irradiated v...

OBJECTIVE To investigate the difference between preoperative radiologic tumor volume (RTV) and postoperative pathologic tumor volume (PTV) in patients who received nephrectomy for renal cell carcinoma (RCC). MATERIALS AND METHODS We reviewed 482 patients who underwent preoperative computed tomography (CT) within 4 weeks before radical or partial nephrectomy for renal cell carcinoma. RTV measu...

ID: 17988 Title: Improve PTV Dose Distribution by Using Spatial Information in IMRT Optimization Purpose: The spatial distribution of radiation dose within the PTV does have clinical significance. For instance, if hot/cold spots in the PTV cannot be avoided, high doses are preferred to be located in the center, and low doses at the peripheries. However, traditional plan optimization models for ...

Intensity-modulated radiation therapy (IMRT) has recently become popular in Japan. Prostate cancer is indisputably one of the main targets of IMRT. However, the current status and interfacility differences in dose-prescription policies for prostate IMRT are unknown. Therefore, a nationwide survey of 43 institutions that had implemented prostate IMRT was conducted by sending a questionnaire rega...

The aim of this meta-analysis was to explore the effects of tumor volume (TV) and percent tumor volume (PTV) on biochemical recurrence (BCR) after radical prostatectomy (RP). An electronic search of Medline, Embase and CENTRAL was performed for relevant studies. Studies evaluated the effects of TV and/or PTV on BCR after RP and provided detailed results of multivariate analyses were included. C...

Abstract Objectives This study aimed to identify high-risk factors for high cardiac radiation exposure, based on anatomical measurements taken from planning CT images of patients with left-sided breast cancer who underwent breast-conserving surgery and received radiotherapy. Methods We retrospectively analyzed 45 whole-breast radiotherapy, either under free breathing (27/45) or deep inspiratory...

Aim: To evaluate the dosimetric outcomes of two different three dimensional conformal radiation therapy (3D-CRT) of concomitant boost delivery to the intact breast. Methods: Ten patients were evaluated using two standard opposed tangents conformal to the whole breast PTV, plus a pair of wedged fields conformal to the boost PTV; all fields have the same isocenter, placed in the whole breast plan...