BACKGROUND Childhood psychotic symptoms have been used as a subclinical phenotype of schizophrenia in etiological research and as a target for preventative interventions. However, recent studies have cast doubt on the specificity of these symptoms for schizophrenia, suggesting alternative outcomes such as anxiety and depression. Using a prospective longitudinal birth cohort we investigated whet...

Evidence from clinical patient populations indicates that affective dysregulation is strongly associated with reality distortion, suggesting that a process of misassignment of emotional salience may underlie this connection. To examine this in more detail without clinical confounds, affective regulation-reality distortion relationships, and their clinical relevance, were examined in a German pr...

CONTEXT Methamphetamine is associated with psychotic phenomena, but it is not clear to what extent this relationship is due to premorbid psychosis among people who use the drug. OBJECTIVE To determine the change in the probability of psychotic symptoms occurring during periods of methamphetamine use. DESIGN Longitudinal prospective cohort study. A fixed-effects analysis of longitudinal pane...

Joel E. Streim, MD (Chair) J. Michael Ryan, MD Atypical Antipsychotics for the Management of Patients With Dementia and Psychotic Symptoms On August 18 and 19, 2003, two symposia entitled “Effective Management of Patients With Dementia and Psychotic Symptoms” and “Atypical Antipsychotic Drugs for the Treatment of Psychotic Symptoms of Dementia” were presented at the 11th International Congress ...

BACKGROUND Cannabis use appears to exacerbate psychotic symptoms and increase risk of psychotic relapse. However, the relative contribution of cannabis use compared with other risk factors is unclear. The influence of psychotic symptoms on cannabis use has received little attention. AIMS To examine the influence of cannabis use on psychotic symptom relapse and the influence of psychotic sympt...

We present a case of a middle-aged male patient with a long history of conversion disorder and histrionic personality, who presented with newly onset psychotic symptoms while being engaged to treatment with a community mental health team in a primary care setting. The symptoms could not be attributed to an organic cause. After a short course of olanzapine treatment which caused adverse effects,...

BACKGROUND Immigration status is a significant risk factor for psychotic disorders, and a number of studies have reported more severe positive and affective symptoms among immigrant and ethnic minority groups. We investigated if perceived discrimination was associated with the severity of these symptoms among immigrants in Norway with psychotic disorders. METHODS Cross-sectional analyses of 9...

OBJECTIVE To identify the cross-national prevalence of psychotic symptoms in the general population and to analyze their impact on health status. METHOD The sample was composed of 256,445 subjects (55.9% women), from nationally representative samples of 52 countries worldwide participating in the World Health Organization's World Health Survey. Standardized and weighted prevalence of psychoti...

The classifications of the psychiatric disorders that we manage1 contemplate the possibility of positive psychotic symptoms being present in bipolar disorder. They describe how these symptoms can appear in both the depressive and the manic and the mixed phases, how they can be congruent or incongruent with patient mood and, lastly, how they can adopt the form of delirium and/or hallucinations. ...