Section of Molecular Neuropharmacology (B.B.F., J.H.), Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden; Behavioural Biology Laboratory (K.B.), Swiss Federal Institute of Technology, Zürich, Switzerland; INSERM U 398 (A.N.), Faculté de Médecine, Strasbourg Cedex, France; Department of Psychopharmacology (E.E.Z.), Valdman Institute of Pharmacology, Pavlov Medic...

Research in psychopharmacology for children and adolescents is fraught with ethical problems and tensions. This has practical consequences as it leads to a paucity of the research that is essential to support the treatment of this vulnerable group. In this article, we will discuss some of the ethical issues which are relevant to such research, and explore their implications for both research an...

Exposure of the general population to a 1:4 lifetime risk of disabling anxiety has inspired generations of fundamental and clinical psychopharmacologists, from the era of the earliest benzodiazepines (BZ) to that of the selective serotonin reuptake inhibitors (SSRIs) and related compounds, eg, the serotonin and norepinephrine reuptake inhibitors (SNRIs). This comprehensive practical review summ...

Psychotropic and other drugs can alter brain mechanisms regulating the formation, storage, and retrieval of different types of memory. These include "off label" uses of existing drugs and new drugs designed specifically to target the neural bases of memory. This paper discusses the use of beta-adrenergic antagonists to prevent or erase non-conscious pathological emotional memories in the amygda...

addicts emerging not from the traditional milieu changes. As pharmaceutical companies gained of the urban underclass but from the white control over research and the subsequent suburban middle-classes, and from the 1980s marketing of drug therapies, the faith in science with the disastrous spread of HIV/AIDS, gave increasingly meant a faith in pharmaceutical impetus to new non-medical movements...