Introduction Psychedelic-assisted therapy with psilocybin has shown promise in Phase 2 trials for alcohol use disorder (AUD). Set and setting, particularly factors facilitating a connection nature, may positively influence the psychedelic experience therapeutic outcomes. But to date, randomized controlled of interventions enhance set setting psychedelic-assisted are lacking. Methods This was pi...

Many people remember vaguely that LSD and other psychedelic drugs were once used experimentally in psychiatry, but few realize how much and how long they were used. This was not a quickly rejected and forgotten fad. Between 1950 and the mid-1960s there were more than a thousand clinical papers discussing 40,000 patients, several dozen books, and six international conferences on psychedelic drug...

The current study examined QEEG power and coherence of ayahuasca experiences with two experienced participants in a Brazilian jungle setting. An exploratory case series design was adopted for naturalistic field research. EEGs recorded during visual imagery was compared to eyes-closed baselines. The most important findings were increases in global EEG coherence in the 36-44 Hz and 50-64 Hz frequ...

~ Abstract-Following Alben Hofmann'sdiscoven'_QU,sp's psychoactive properties in 1943. and previous to their ~lIlingJls.controlledsubstances. the psychedelic drugs were widely studied­ (]) '~.~~!em~~if~t:F:0ll!~~~:~d,b~1ldr!;dS,;ptp-'~!~,4is~¥~~.t¥i.~,~~:~,~~_;t~~~~~,~f\!.!~;S8':· Thii'<illset9i1iicin that the frightening experience ofaeliriiimiremens som2jtim led alcoholics to moderate their a...