A thermodynamic dataset was developed for the quinary Ti-Si-B-C-N system. The phase modeling includes all carbides, nitrides, carbonitrides, borides and silicdes which can be used as high temperature structural materials. The CALPHAD approach is used to calculate high-temperature phase reactions in the ternary and quaternary subsystems. The phase stabilities can be derived. All types of phase d...

results the results showed that the maximum oil was incorporated in microemulsion system that contained surfactant to cosurfactant ratio of 4:1. the mean droplet size range of microemulsion formulation was in the range of 5.09 to 159 nm, and its refractory index (ri) and ph were 1.44 and 7, respectively. viscosity range was 57-226 cps. drug release profile showed that 48.18% of the drug release...

The phase properties of lipids have far-reaching consequences in membrane biology. Their influence ranges from domain formation in intact biomembranes to membrane protein reconstitution and crystallization. To exploit phase behavior in the spirit of rational design, it is imperative that the rules relating lipid molecular structure and liquid crystal or mesophase behavior be established. Phase ...

BACKGROUND The objective of this study was to evaluate fluid-bed coating as a new technique to prepare a pellet-based solid self-nanoemulsifying drug delivery system (SNEDDS) using cyclosporin A as a model of a poorly water-soluble drug. METHODS The rationale of this technique was to entrap a Liquid SNEDDS in the matrix of the coating material, polyvinylpyrrolidone K30, by fluid-bed coating. ...

This paper provides an evaluation of the effectiveness of using the high throughput combinatorial approach for preparing phase diagrams of thin film and bulk materials. Our evaluation is based primarily on examples of combinatorial phase diagrams that have been reported in the literature as well as based on our own laboratory experiments. Various factors that affect the construction of these ph...

BACKGROUND The increased incidence of inflammatory diseases has necessitated the need to search for new topical dosage form of dexamethasone. OBJECTIVES The purpose of the present study was the preparation and evaluation of novel microemulsion as a topical delivery system for dexamethasone by mixing appropriate amount of surfactant including Tween 80 and Labrasol, cosurfactant such as capryol...

This paper highlights the importance of software maintenance, specifically the UML (Unified Modeling Language) diagrams, created and changed, especially during the tasks of analysis and design of software. The main idea of this paper is to formalize the software maintenance phase in order to motivate the maintenance documentation of these diagrams taking into account a knowledge base which repr...