Glaucoma is the most common cause of blindness, which significantly reduces quality life. Most glaucoma cases are primary glaucoma; nevertheless, many patients suffer from caused by drugs, such as corticosteroids. A comprehensive review risks associated with corticosteroid-induced limited. Therefore, we used Japanese Adverse Drug Event Reporting Database (JADER) published Pharmaceuticals and Me...

background: glaucomatous neuropathy is a type of cell death due to apoptosis. the p53 gene is one of the regulatory genes of apoptosis. recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (poag) has been studied in some ethnic groups. this study is the first association analysis of poag and p53 codon 72 polymorphism in iranian patients...

objective: to compare the frequency of helicobacter pylori (h. pylori) infection in subjects with primary open angle glaucoma (poag) vs controls. methods: in a case-control study, 44 patients with primary open angle glaucoma and 79 patients with senile cataract (control group) were investigated for serum level of anti-h. pylori antibody using the enzyme-linked immunosorbant assay (elisa) method...

Objective(s):Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. Glutathione S-transferases (GSTs) are members of multigenic family, which have important role in cells as an antioxidant. In the present study, we examined the polymorphism of GSTT1 and GSTM1 deletion genotypes (T0M1, T1M0, and T0M0) in 100 Glaucoma patients (41with pr...

Introducción: Los objetivos de este trabajo son revisar y resumir los datos publicados hasta el momento que relacionen uso estatinas con riesgo aparición o agravamiento glaucoma plantear una hipótesis explique efectos protectores las su asociación un menor glaucoma.
 Método: se realizó revisión en PubMed usando términos “statins, hmg coa” “hmg coa inhibitors” “glaucoma” “open angle glaucom...

purpose : to evaluate central corneal thickness (cct) in patients with juvenile glaucoma and compare it with that of normal individuals methods : a prospective, case-control study was performed on 80 eyes with juvenile glaucoma who attended glaucoma clinic in farabi eye hospital, tehran, iran and 107 clinically normal healthy eyes. standard automated perimetry (sap) was performed for all the pa...

background: glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. in patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. death of the trabecular meshwork cells may be a result of apoptosis. objective: to investigate the aqueous humor levels of soluble fas (sfas) and fas-ligand (sfasl) in ...