The decrease in the proliferative response of lymphocytes is one of the most evident among the age-related changes of the immune system. This has been linked to a higher risk of mortality in both humans and experimental animals. However, long-lived individuals, in spite of optimally maintaining most of the functions of the immune system, also seem to show an impaired proliferative response. Thu...

Three patients developed symptoms suggestive of acute schizophrenia. In each case there were no abnormal neurological findings on admission to hospital. Within a few days clinical evidence of encephalitis became apparent, and appropriate treatment was given. Only one patient made a full recovery.

asri@interchange Summary Periprosthetic fractures are increasing in number and complexity. Appropriate precautions should be taken to prevent these fractures. A systematic approach is needed in the form of detailed assessment of the fracture, stability of the implant and the available bone stock for planning an appropriate treatment. The treatment options described in this article can be used a...

Traditional views on facial aging and associated therapies focused on soft tissue descent and skin texture changes. Recently, revolumization for age-related lipoatrophy has become increasingly popular. Researchers are now reporting objective studies examining processes of structural and volumetric changes with age in increasing frequency as well. To better understand and treat facial aging, the...

a frequency domain dynamic analysis is needed to obtain the response of structures constructed on a system of base isolators on flexible soil when subjected to earthquake ground motion. in such systems, the lateral stiffness of the base isolators is so small, compared to the structural stiffness, that in an earthquake attack the fundamental vibration mode dominates the response. with this in mi...

Some examples of absurd uniformly minimum variance unbiased estimators are discussed. Two reasons, argued in the literature, for having such estimators are lack of enough information in the available data and property of unbiasedness. In this paper, accepting both of these views, we show that an appropriate choice of loss function using a general concept of unbiasedness leads to risk unb...

Scheduling theories for xed-priority scheduling are now suuciently mature that a genuine engineering approach to the construction of hard real-time systems is possible. In this chapter we review recent advances. A exible computational model is adopted that can accommodate periodic and sporadic activities, diierent levels of criticality, process interaction and blocking, cooperative scheduling (...

BACKGROUND Improvised explosive devices are a common feature of recent asymmetric conflicts and there is a persistent landmine threat to military and humanitarian personnel. Assessment of injury risk to the spine in vehicles subjected to explosions was conducted using a standardized model, the Dynamic Response Index (DRI). However, the DRI was intended for evaluating aircraft ejection seats and...