Most thyroglossal duct cysts are located at or very close to the midline. They generally manifest as painless neck swellings, and they move on protrusion of the tongue and during deglutition. We describe a case of thyroglossal duct cyst that was unusual in that the cyst was located far from the midline, it did not move on protrusion of the tongue, and it was associated with symptoms of dysphagi...

The management of disc protrusion is multidisciplinary. In the midway between conservative treatment and open surgery are minimal invasive procedures. Nucleoplasty is a new treatment of discogenic leg pain using bipolar radiofrequency device for vaporising a small volume of nucleus pulposus. Percutaneous removal of nuclear tissue is thought to lower nuclear pressure, thereby reducing nerve root...

This critical review examines the orofacial and speech effects of palatal plate therapy on children with Down syndrome. Multiple studies, varying in style design, have investigated this topic. Features analyzed in these studies include tongue protrusion, mouth occlusion, tooth eruption, sucking habits, articulation and facial expression. Overall, there is suggestive evidence that palatal plate ...

In order to reduce the protrusion height and increase strength of clinched joint, a two-step clinching method was investigated in present study. The whole process contains two steps. first step is used produce one-step joints, second press joints joining strength. influences steps sheet thicknesses on mechanical properties joint were investigated. main failure mode all tests neck fracture mode....

This report describes the nonsurgical treatment of a patient with skeletal Class II protrusion and severe crowding. A 20-year-old woman presented with the chief complaint of lip protrusion and crowding. To correct the Class II relationship, severe crowding, and lip protrusion, distal movement of the maxillary first molars using indirect miniscrew anchorage and nickel-titanium coil springs, alon...

While the molecular and biophysical mechanisms underlying cell protrusion on two-dimensional substrates are well understood, our knowledge of the actin structures driving protrusion in three-dimensional environments is poor, despite relevance to inflammation, development and cancer. Here we report that, during chemotactic migration through microchannels with 5 μm × 5 μm cross-sections, HL60 neu...

Cell migration requires the coordinated spatiotemporal regulation of actomyosin contraction and cell protrusion/adhesion. Nonmuscle myosin II (MII) controls Rac1 and Cdc42 activation, and cell protrusion and focal complex formation in migrating cells. However, these mechanisms are poorly understood. Here, we show that MII interacts specifically with multiple Dbl family guanine nucleotide exchan...

Each cell within a polarized epithelial sheet must align and correctly position a wide range of subcellular structures, including actin-based dynamic protrusions. Using in vivo inducible transgenes that can sense or modify Rac activity, we demonstrate an apicobasal gradient of Rac activity that is required to correctly form and position distinct classes of dynamic protrusion along the apicobasa...