objective: the theraputic exercise is regarded as one of the most important theraputic interventions in the chronic low back pain patients. stabilization exercise is among the most significant practical ones in these patients. the study of the effects of these exercises on the variability of trunk muscles postural strategies and the ability in normalizing these strategies are among the uncertai...

having knowledge about genetic relationships among accessions is necessary for developing breeding strategies to produce improved cultivars. in present study, genetic diversity and inter-relationship among 29 genotypes of citrus were comparatively analyzed using morphological and rapd markers. significant variability was observed among citrus genotypes for 61 quantitative and qualitative morpho...

researchers suggested that the individual fit test be conducted to estimate the protection effectiveness of workers’ hearing protection device (hpd) while working. practically, it is convenient to conduct single, instead of multiple, fit test measurement. this study examined if a single trial of earplug fit test can represent multiple performances. additionally, it investigated how much noise e...

this research was conducted to investigate spatial variability and estimate tree attributes in a plantation forest in the caspian region of iran using geostatistical analysis. sampling was performed based on a 50m?125m systematic grid in a maple stand (acer velutinum boiss) 18 years of age using circular samples of 200m2 area. totally, 96 sample plots were measured in 63 hectares and 14.25 hect...

In small volumes, the kinetics of filamentous protein self-assembly is expected to show significant variability, arising from intrinsic molecular noise. This is not accounted for in existing deterministic models. We introduce a simple stochastic model including nucleation and autocatalytic growth via elongation and fragmentation, which allows us to predict the effects of molecular noise on the ...

Marketed drugs frequently perform worse in clinical practice than in the clinical trials on which their approval is based. Many therapeutic compounds are ineffective for a large subpopulation of patients to whom they are prescribed; worse, a significant fraction of patients experience adverse effects more severe than anticipated. The unacceptable risk-benefit profile for many drugs mandates a p...

MOTIVATION The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously. To avoid quantification bias due to mis-specification of commonly used parametric models, a nonparametric approach based on monotone response curves may be used. The existing methods, however, aggregate the protein concentratio...

Global coevolutionary models of homologous protein families, as constructed by direct coupling analysis (DCA), have recently gained popularity in particular due to their capacity to accurately predict residue-residue contacts from sequence information alone, and thereby to facilitate tertiary and quaternary protein structure prediction. More recently, they have also been used to predict fitness...

In the comparison of DNA and protein sequences between species or between paralogues or among individuals within a species or population, there is often some indication that different regions of the sequence are divergent or polymorphic to different degrees, indicating differential constraint or diversifying selection operating in different regions of the sequence. The problem is to test statis...