The property of an amino acid is different according to the variation of protein secondary structure. Each central amino acid corresponds to several conditional probability distributions of amino acid on the specific positions surrounding it. Based on this property, we get amino acid distance matrices for helix, sheet, coil and turn conformation. It is observed that, for different protein secon...

The topology of most experimentally determined protein domains is defined by the relative arrangement of secondary structure elements, i.e. α-helices and β-strands, which make up 50-70% of the sequence. Pairing of β-strands defines the topology of β-sheets. The packing of side chains between α-helices and β-sheets defines the majority of the protein core. Often, limited experimental datasets re...

background: rotaviruses (rv) are important viral diarrheal agents in calves. vaccination is an optimum measure to prevent bovine rotaviruses (brv) infection. however, little research on brv vp7 vaccine has been done and currently there is no brv vaccine. objective: to prepare a subunit vaccine of brv and investigate its efficacy. methods: total rna was extracted from ma104 cells infected with b...

background: mushroom tyrosinase a potent candidate in clinical studies known as polyphenol oxidase, is a metaloenzyme from the oxidase superfamily widely distributed from lower to higher life forms. it plays a crucial role in sclerotization of exoskeleton in insects, also responsible for skin pigmentation in mammalians. objective: in this study, after reconstitution of mt by some metal ions, th...