A septic loosening of orthopaedic implants is usually attributed to the action of wear debris from the prosthesis. Recent studies, however, have also implicated physical pressures in the joint as a further cause of loosening. We have examined the role of both wear debris and pressure on the secretion of two chemokines, MIP-1alpha and MCP-1, together with M-CSF and PGE2, by human macrophages in ...

Background: Aseptic loosening of massive bone tumour implants remains one of the major causes of prosthesis failure. Question: The hypothesis of this study was that an osteointegrated hydroxyapatite (HA) coated collar would reduce the incidence of aseptic loosening around the cemented intramedullary stem in distal femoral bone tumour prostheses. Methods: Twenty-two patients were pair matched in...

Chondrosarcoma is a malignant cartilage-forming neoplasm. It is difficult to treat because of resistance to both chemotherapy and radiation, making wide local excision the only treatment. This report presents an active, 43 year-old man who was diagnosed with recurrent clear cell chondrosarcoma of the proximal left femur, previously reconstructed with a total hip prosthesis, extending to the wei...

BACKGROUND Treatment of the sequelae of congenital high luxation of the hip joint is a major challenge in prosthetic surgery, demanding from the operator thorough familiarity with the problem and experience in hop reconstructive surgery. MATERIAL AND METHOD The results of 4 years observation, of the treatment of 14 woman in the average age of 38 years old with 18 hip joints with congenital hi...

In order to determine the magnitude of temperature increases in resurfaced hips, temperature sensors were placed percutaneously in both hip joints of 12 volunteer patients who had 1 or both joints resurfaced. Temperature recordings were made with patients at rest (baseline) and after patients walked for 20 and 60 minutes. The hip resurfacing procedures were performed 12 to 36 months prior to th...

OBJECTIVE To analyze the outcomes of total elbow arthroplasty in the treatment of elderly type C distal humeral fractures and discuss the clinic efficacy. METHODS 8 cases of elderly type C distal humeral fractures, Male was in one case, female in seven cases, and the average age was 66.5 years (60-81). All cases were closed fractures because of falling and none had associated injuries. Accord...

The surgical treatment of glenohumeral arthritis with rotator cuff deficiency is a difficult challenge. Hemiarthroplasty, the standard treatment at this time, is associated with satisfactory results in a ‘‘limited goals’’ perspective, but often the clinical results are unpredictable. Elevation after hemiarthroplasty approximately 90 . Pain relief can be inconsistent and can deteriorate over tim...

The aim of this study was to evaluate the treatment of isolated septic acetabular cup loosening without involvement of the prosthesis stem by insertion of an antibiotic-loaded spacer head and stem retention. Between 1999 and 2008, 13 patients (5 men, 8 women, mean age 69 years) were treated according to this regimen. S. epidermidis and S. aureus were the two most commonly identified pathogens. ...