PURPOSE To evaluate the risk of prostate cancer (PCa) on a third prostate biopsy in a group of patients with two consecutive diagnoses of high grade intraepithelial neoplasia (HGPIN). MATERIALS AND METHODS From November 2004 to December 2007, patients referred to our clinic with a PSA ! 4 ng/ml or an abnormal digital rectal examination (DRE) were scheduled for trans-rectal ultrasound (TRUS) g...

PURPOSE Recent studies have suggested that the percent of positive cores in the prostate needle biopsy is a significant predictor of outcome among men undergoing radical prostatectomy or radiation therapy for prostate cancer. We evaluate whether either percent of cores with cancer or percent of cores positive from the most and least involved side of the prostate needle biopsy was associated wit...

We present the proof-of-concept prototype of a prostate biopsy robot to be used inside a conventional high-field MRI scanner. A three degree-offreedom (DOF) mechanical device translates and rotates inside the rectum and enters a needle into the body, and steers the needle to a target point pre-selected by the user. The device is guided by real-time images from the scanner. Networked computers p...

In this paper is presented an Augmented Reality (AR) system used for training the urologist to insert the biopsy needle using a serial robot as a case study. The AR based training set-up consists of a large screen projection system for the visualisation of the colocated environment and the software that uses one static single-camera marker tracking to colocate the virtual patient in the robot w...

We report a case of primary mucosa-associated lymphoid tissue (MALT) lymphoma of the prostate. A 67-year-old man presented with urinary obstruction and an elevated prostate-specific antigen (PSA) level. A physical examination revealed mild prostate enlargement and no lymphadenopathy. A needle biopsy and immunohistochemical studies of the prostate were performed, which revealed marginal zone B-c...

Transrectal ultrasonography (US)-guided biopsy is the standard approach for histopathologic diagnosis of prostate cancer. However, this technique has multiple limitations owing to the operator's inability in most cases to directly visualize and target prostate lesions. Magnetic resonance (MR) imaging of the prostate overcomes many of these limitations by directly depicting areas of abnormality ...

Objectives To assess the feasibility of a 2 generation MRcompatible, remote-controlled manipulator (RCM) as an aid to perform MR-guided transrectal prostate biopsy in males with suspicion of prostate cancer (PCa). Methods This prospective phase I study was approved by the local ethical committee and written informed consent was obtained from each patient. Twenty patients with ≥1 cancer suspicio...

PURPOSE To assess the pain intensity of patients administered midazolam and fentanyl citrate before undergoing transrectal ultrasound-guided prostate biopsy. MATERIALS AND METHODS This was a study in patients with different indications for prostate biopsy in whom 5 mg of midazolam and 50 µg of fentanyl citrate was administered intravenously 3 minutes before the procedure. After biopsy, pain w...

The instrument described here consists of a special syringe on which sharp cutting needles of various sizes are mounted. These produce undistorted biopsy specimens. Suction is used only to retain the specimen within the needle, and the cleancut cylinder of tissue is quite unlike that obtained by aspiration. Gillman and Gillman&2 used this principle for their liver biopsy instrument. We have ret...

Giant multilocular prostatic cystadenomas are rare tumors (only 20 cases reported so far) that may present as large abdominal masses causing symptoms of urinary frequency and urgency. Routine needle core biopsy can be misleading and reveals only benign prostatic tissue. We report the case of a 61-year-old male who presented with a large abdomino-pelvic mass and symptoms of an enlarged prostate....