Prognostics and Health Management (PHM) is a methodology that permits the assessment of product reliability and the prediction of remaining useful life (RUL) under life-cycle conditions through continuous monitoring. This paper addressed a unique use of PHM for business warranties. PHM is able to help understand what went wrong quickly and exactly in a product. PHM will assist companies to make...

It is common for large population-based surveys to select a sample from a population using a complex design. A simulation study was conducted to compare the estimates from the stratified proportional hazards model with the weighted estimates of the Binder method, when a stratified random sample of the population is used. The SAS PHREG procedure performs regression analysis of survival data base...

Simulation studies present an important statistical tool to investigate the performance, properties and adequacy of statistical models in pre-specified situations. One of the most important statistical models in medical research is the proportional hazards model of Cox. In this paper, techniques to generate survival times for simulation studies regarding Cox proportional hazards models are pres...

To understand the roles of secretory peptides in developmental signaling, we have studied Drosophila mutant for the gene peptidylglycine alpha-hydroxylating monooxygenase (PHM). PHM is the rate-limiting enzyme for C-terminal alpha-amidation, a specific and necessary modification of secretory peptides. In insects, more than 90% of known or predicted neuropeptides are amidated. PHM mutants lack P...

Case studies were conducted using a stochastic model to predict the life cycle cost impact associated with the application of prognostic health management (PHM) to helicopter avionics. The life cycle costs of systems that assumed unscheduled maintenance and fixed-interval scheduled maintenance were compared to the costs of precursor-to-failure and life consumption monitoring PHM approaches, and...