The probability distribution of the proper delay times during scattering on a chaotic system is derived in the framework of the random matrix approach and the supersymmetry method. The result obtained is valid for an arbitrary number of scattering channels as well as arbitrary coupling to the energy continuum. The case of statistically equivalent channels is studied in detail. In particular, th...

The phytohormone auxin is involved in virtually every aspect of plant growth and development. Through polar auxin transport, auxin gradients can be established, which then direct plant differentiation and growth. Shade avoidance responses are well-known processes that require polar auxin transport. In this study, we have identified a mutant, shade avoidance 4 (sav4), defective in shade-induced ...

Candida albicans is an opportunistic fungus responsible for the majority of systemic fungal infections. Multiple factors contribute to C. albicans pathogenicity. C. albicans strains lacking CaArv1 are avirulent. Arv1 has a conserved Arv1 homology domain (AHD) that has a zinc-binding domain containing two cysteine clusters. Here, we explored the role of the CaAHD and zinc-binding motif in CaArv1...

ESO 4m class telescope and VLT deep imaging of the isolated neutron star RXJ0720.4-3125 reveals a proper motion of μ = 97 ± 12mas/yr and a blue U-B color index. We show that a neutron star atmosphere model modified to account for a limited amount of hydrogen on the star’s surface can well represent both the optical and X-ray data without invoking any additional components. The large proper moti...

The biogenesis of nuclear pore complexes (NPCs) represents a paradigm for the assembly of high-complexity macromolecular structures. So far, only three integral pore membrane proteins are known to function redundantly in NPC anchoring within the nuclear envelope. Here, we describe the identification and functional characterization of Pom33, a novel transmembrane protein dynamically associated w...

We show that s-term DNF formulas can be learned under the uniform distribution in quasi-polynomial time with statistical queries of tolerance Ω(ε/s). The tolerance improves on the known tolerance Ω(ε/s) and is optimal with respect to its dependence on the error parameter ε. We further consider the related model of learning with proper distance queries and show that DNF formulas can be learned u...

Species distribution models (SDMs) are often used to predict the impact of climate change on future species. However, application species-level SDMs ignores intraspecific variation and can be problematic. The aim study was incorporate information into compare predictions subspecies- in a widespread African tree species, Sclerocarya birrea (marula). We bioclimatic variables terrain roughness ind...

Observational studies support a neuroprotective role of hormone therapy (HT) in the perimenopause, with hippocampal size being a widely used biomarker. We investigated the effect of HT started before the onset of menopause and lasting for at least 3 years on hippocampal volume and shape in 80 postmenopausal women and 80 controls matched on age and intracranial volume taken from a large communit...

The main result implies that a proper convex subset of an irreducible higher rank symmetric space cannot have Zariski dense stabilizer.

The research reported in this thesis has been carried out under the auspices of SIKS, the Dutch Research School for Information and Knowledge Systems. Preface Here I present the result of my last four years of hard work. When I started the process I had the idea to learn more and to satisfy my curiosity. In the end I think I can say that I succeeded. There is however much more to a Ph.D. than s...