Detection of gamma-ray bursts (GRBs) from redshifts z ∼> 7 would open a new window into the earliest epoch of cosmic star formation. We construct separate star formation histories at high redshifts for normal (Pop I and II) stars, and for predominantly massive (Pop III) stars. Based on these separate histories, we predict the GRB redshift distribution to be observed by the Swift mission. Regard...

Over the last few years, there have been an increasing number of gaming operators that have incorporated on-screen pop-up messages while gamblers play on slot machines and/or online as one of a range of tools to help encourage responsible gambling. Coupled with this, there has also been an increase in empirical research into whether such pop-up messages are effective, particularly in laboratory...

Pop-refinement is an approach to stepwise refinement, carried out inside an interactive theorem prover by constructing a monotonically decreasing sequence of predicates over deeply embedded target programs. The sequence starts with a predicate that characterizes the possible implementations, and ends with a predicate that characterizes a unique program in explicit syntactic form. Compared to ex...

BACKGROUND Pelvic organ prolapse (POP) brings major health issues for women, affecting 40% of postmenopausal women, and directly affects bladder and bowel function, as well as quality of life. In light of the projected growth in demand for care for pelvic floor disorders, determining the etiology and progression of POP has important public health implications. MATERIAL AND METHODS Uterosacral l...

Current evidence suggests a multifactorial etiology to pelvic organ prolapse (POP), including genetic predisposition. We conducted a genome-wide association study of POP in African American (AA) and Hispanic (HP) women from the Women's Health Initiative Hormone Therapy study. Cases were defined as any POP (grades 1-3) or moderate/severe POP (grades 2-3), while controls had grade 0 POP. We perfo...

BACKGROUND Lung cancer patients with chronic obstructive pulmonary disease (COPD) have a high risk of developing postoperative pneumonia (POP). This study aims to investigate the impact of COPD on POP and the trends for perioperative bronchial colonisation by micro-organisms. METHODS A retrospective chart review was made for 626 patients who underwent lung cancer surgeries at the Chiba Univer...

Female pelvic floor dysfunction (FPFD) is a complex group of conditions that include urinary incontinence and pelvic organ prolapse (POP). In humans, elastin homeostasis has been implicated in the pathophysiology of FPFD. Lysyl oxidase-like 1 knockout (LOXL1-KO) mice demonstrate abnormal elastic fiber homeostasis and develop FPFD after parturition. We compared the lower urogenital tract (LUT) a...

BACKGROUND Pelvic organ prolapse (POP) is a major health problem in adult women that involves many factors. No proteomic analysis has been conducted exclusively in POP patients. This study aimed to identify the differential expression of proteins that may be involved in POP by proteomic analysis. METHODS Samples of the uterosacral ligament (USL) were collected from five POP patients and five ...

OBJECTIVE Postoperative pneumonia (POP) is common and results in prolonged hospital stays, higher costs, increased morbidity and mortality. However, data on the incidence and risk factors of POP after oral and maxillofacial surgery are rare. This study aims to identify perioperative risk factors for POP after major oral cancer (OC) surgery. METHODS Perioperative data and patient records of 33...