نتایج جستجو برای: prognostic

تعداد نتایج: 111146  

2011
Thomas Karn Lajos Pusztai Uwe Holtrich Takayuki Iwamoto Christine Y. Shiang Marcus Schmidt Volkmar Müller Christine Solbach Regine Gaetje Lars Hanker Andre Ahr Cornelia Liedtke Eugen Ruckhäberle Manfred Kaufmann Achim Rody

BACKGROUND Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers. The identification of prognostic signatures from TNBC cohorts was limited in the past due to small sample sizes. METHODOLOGY/PRINCIPAL FINDINGS We assembled all currently publically available TNBC gene expression datasets generated on Af...

2016
Wenjing Tian Le Wang Lili Yuan Wenming Duan Wenhui Zhao Shuhuai Wang Qingyuan Zhang

The aim of this study was to establish a prognostic risk model for patients with triple negative breast cancer (TNBC). A total of 278 specimens of human TNBC tissues were investigated by immunohistochemistry for growth-arrest specific protein 6 expression, infiltrations of stromal natural killer cells and tumor-associated macrophages. According to their prognostic risk scores based on the model...

Journal: :Acta orthopaedica Scandinavica. Supplementum 2004
Jacob Engellau

In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. The tissue-preserving, high throughput tissue microarray (TMA)...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1998
J P Peyrat L Vanlemmens J Fournier G Huet F Révillion J Bonneterre

We measured the levels of p53 and urokinase-type plasminogen activator (uPA) in 634 tumor tissues from 634 different node-negative primary breast cancer patients who underwent locoregional surgery in the Center Oscar Lambret between July 1989 and September 1994. p53 and uPA were assayed using commercially available kits in cytosols prepared for estradiol receptor (ER) and progesterone receptor ...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005
Tarek M Mekhail Rony M Abou-Jawde Gabriel Boumerhi Sareena Malhi Laura Wood Paul Elson Ronald Bukowski

PURPOSE To validate the Motzer et al prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma (RCC) and to identify additional independent prognostic factors. PATIENTS AND METHODS Data were collected on 353 previously untreated metastatic RCC patients enrolled onto clinical trials between 1987 and 2002. RESULTS Four of the five prognostic f...

2016
Heung-Chul Park Moon-Young Kim Chul-Hwan Kim

OBJECTIVES Many studies have examined histopathological factors and various prognostic scores related to inflammation to predict outcomes. Here, we examined the prognostic value of the C-reactive protein/albumin (CRP/alb) ratio in oral squamous cell carcinoma (OSCC). MATERIALS AND METHODS This retrospective study included 40 patients with OSCC. Using univariate and multivariate analyses, we f...

Journal: :Revista portuguesa de pneumologia 2013
A Inal M Kucukoner M A Kaplan Z Urakci N Nas M Guven Z Dostbil S Altindag A Isikdogan

BACKGROUND Although a number of studies in patients with a variety of malignant tumors have shown that metabolic activity on fluorine-18 deoxyglucose positron emission tomography computed tomography ((18)F-FDG-PET/CT) is correlated with survival, there are few studies about the impact of (18)F-FDG-PET/CT for survival in small cell lung cancer (SCLC) patients. There is still some ambiguity as to...

2015
Guannan Wu Yanwen Yao Cuiqing Bai Junli Zeng Donghong Shi Xiaoling Gu Xuefei Shi Yong Song

BACKGROUND The neutrophil to lymphocyte ratio (NLR) was recently shown to be a remarkable prognostic factor in tumors. Moreover, some studies have indicated that the combination of NLR and platelet to lymphocyte ratio (PLR) could be a better prognostic factor. As the combined prognostic value of NLR and PLR in non-small cell lung cancer (NSCLC) is not clear, we conducted this study to explore t...

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