conclusions polymorphism in the hemochromatosis gene may confer some degree of risk for hcv infection, and individuals carrying the h and c alleles may be susceptible to this disease; however, a larger sample of hcv patients and healthy individuals may be necessary to further illustrate the role of these polymorphisms in hcv. patients and methods hfe gene polymorphisms were examined in a total ...

background: although the cox proportional hazard regression is the most popular model for analyzing the prognostic factors on survival of cancer patients, under certain circumstances, parametric models estimate the parameter more efficiently than the cox model.  the aim of this study was to compare the cox regression model  with parametric models in patients with gastric cancer who registered a...

Purpose. Validation of a Canadian three-tiered prognostic model (survival prediction score, SPS) in Norwegian cancer patients referred for palliative radiotherapy (PRT), and evaluation of age-dependent performance of the model. Patients and Methods. We analyzed all 579 PRT courses administered at a dedicated PRT facility between 20.06.07 and 31.12.2009. SPS was assigned as originally described,...

A general framework for probabilistic fatigue damage prognosis using maximum entropy concept is proposed in this paper. The fatigue damage is calculated using a physics-based crack growth model. Due to the stochastic nature of crack growth process, uncertainties arising from the underlying physical model, parameters of the model, and the measurement noise are considered and integrated into this...

Maintenance plays now a critical role in manufacturing for achieving important cost savings and competitive advantage while preserving product conditions. It suggests moving from conventional maintenance practices to predictive strategy. Indeed the maintenance action has to be done at the right time according the component Remaining Useful Life (RUL) assessed by a prognosis process. The accurac...

Diagnosis and prognosis are necessary tasks for system reconfiguration and fault-adaptive control in complex systems. Diagnosis consists of detection, isolation and identification of faults, while prognosis consists of prediction of the remaining useful life of systems. This paper presents an integrated model-based distributed diagnosis and prognosis framework, where system decomposition is use...

BACKGROUND Esophageal squamous cell carcinoma (ESCC) has the highest mortality rates in China. The 5-year survival rate of ESCC remains dismal despite improvements in treatments such as surgical resection and adjuvant chemoradiation, and current clinical staging approaches are limited in their ability to effectively stratify patients for treatment options. The aim of the present study, therefor...

We compared the performance of several prediction techniques for breast cancer prognosis, based on AU-ROC performance (Area Under ROC) for different prognosis periods. The analyzed dataset contained 1,981 patients and from an initial 25 variables, the 11 most common clinical predictors were retained. We compared eight models from a wide spectrum of predictive models, namely; Generalized Linear ...