Fifty-three mature Hereford-cross heifers, which were between day 0 and 3 of the estrous cycle, each had silastic coils containing 2.1 g progesterone inserted into the vagina where they remained for 12 days. Animals were assigned to treatment groups and were injected with (1) 5 mg estradiol benzoate, (2) as (1) + 50 mg progesterone or (3) as (1) + 200 mg progesterone at the time of insertion of...

1. The effect of progesterone on renal haemodynamics and intrarenal sodium handing was evaluated in thirteen normal men on a constant diet. Clearances were measured during maximal water diuresis and again 4-7 days later, this time 3 h after progesterone was given intramuscularly. Seven additional studies were performed 3 days after progesterone administration. Another four tests were performed ...

OBJECTIVE To compare severity of negative mood and physical symptoms between women with different progesterone, allopregnanolone, and pregnanolone plasma concentrations during sequential Hormone Replacement Therapy (HRT) with vaginal progesterone suppositories. DESIGN A randomized, placebo-controlled, double-blind, crossover study. METHOD Postmenopausal women (n=36) with climacteric symptom...

leptin, a circulating 16-kd polypeptide consisting of 167 amino acids, appears to be involved in the body weight homeostasis. moreover leptin plays an important role for the reproductive system, early embryogenesis, and fat metabolism during pregnancy and puberty. significant correlations have been found between leptin and sexual hormones, which is a cytokine and has hormonal properties. the ai...

This study examines the modulation of functional cerebral asymmetries by gonadal hormones in three distinct groups. Young, normally cycling women performed a prototypical left (lexical decision) and two prototypical right-hemispheric tasks (figural comparison and face discrimination) during the low steroid menses and the high steroid midluteal phase. Saliva progesterone levels were measured wit...

According to a dominant view, the approximate number system (ANS) is the foundation of symbolic math abilities. Due to the importance of math abilities for education and career, a lot of research focuses on the investigation of the ANS and its relationship with math performance. However, the results are inconsistent. This might be caused by studies differing greatly regarding the operationaliza...

Background: Progesterone, one of a class neurosteroids, has been linked to seizure control. However, the pharmacokinetics progesterone and its active metabolite, allopregnanolone, have never investigated among patients with drug-resistant epilepsy (DRE). Objective: To investigate progesterone, 400 mg micronized per oral every 12 hours for three months, DRE as an add-on therapy The pharmacokinet...