introduction: we have recently reported the presence of two potassium currents with 598 and 368 ps conductance in the rough endoplasmic reticulum (rer) membrane. the 598 ps channel was voltage dependent and atp sensitive. however, the 368 ps channel was rarely observed and its identity remained obscure. since cationic channels in intracellular organelles such as mitochondria and rer play import...

Where f denotes Doppler Frequency, τ denotes multipath propagation delay, S (f,τ) denotes the scattering function. In a Power Delay Profile plot, the signal power of each multipath is plotted against their respective propagation delays. A sample power delay profile plot, shown below, indicates how a transmitted pulse gets received at the receiver with different signal strength as it travels thr...

Abstract This paper deals with the reconstruction of the inlet temperature profile of a melted polyethylene (PE) flowing through an extrusion die. The inverse heat transfer problem is formulated as an optimisation problem by considering both the energy and the Navier-Stokes equations. It is solved by using the conjugate gradient algorithm. Experimental results are presented and show the effect ...

Multiple transmit-and-receive antennas can be used in orthogonal frequency division multiplexing (OFDM) systems to improve communication quality and capacity. In this paper, we present two techniques to improve the performance and reduce the complexity of channel parameter estimation: optimum training-sequence design and simplified channel estimation. The optimal training sequences not only sim...

Our understanding of the evolving clinical profile of primary hyperparathyroidism has changed significantly.Recently substantial insights has been gained into its metabolic bone profile in particular. The epidemiology of primary hyperparathyroidism has fluctuated widely, in large part due to the availability of multi channel chemistry screening. Many patients nowadays are thus discovered throug...

We present a technique to measure the velocity and flow profiles of a nanofluid in a microfluidic channel. Importantly, we extract the flow velocity from a series of standard brightfield images without employing particle tracking or laser-enhanced methods. Our analysis retrieves the flow information from the image structure function of sub-diffraction limited nanoparticles in suspension. We are...

This paper presents spatio-te1nporal channel statistics tabulated during a wideband peer-to-peer measurmnent campaign conducted on the campus of Virginia Tech. Based on over 2500 power-delay profile (PDP) snapshots 1nade at 12 different local area locations, the 1neasured statistics reveal trends about the spatio-tmnporal channel at microwave frequencies that will be particularly useful for des...

Senicapoc, a Gardos channel inhibitor, prevented erythrocyte dehydration in clinical trials of patients with sickle cell disease. We tested the hypothesis that senicapoc-induced blockade of the Gardos channel inhibits Plasmodium growth. Senicapoc inhibited in vitro growth of human and primate plasmodia during the clinical blood stage. Senicapoc treatment suppressed P. yoelii parasitemia in vivo...

In this paper, average frequency correlation and rootmean-squared (rms) delay spread estimation for wireless communication systems are described. A practical algorithm for averaged channel frequency correlation estimation, which can be used for measuring frequency selectivity, is given. Average rms delay spread of the channel is obtained directly from the channel frequency correlation estimate ...

A channel base current model of the current generation (CG) type is introduced to describe both negative and positive first return strokes. The key feature of the model is the association of the slow front of the channel base current waveform with the upward connecting leader. This feature is mathematically represented by a discharge propagation speed profile, which is characterized by an initi...