A three-part mechanism is proposed for the induction of Alzheimer’s disease: (1) decreased blood lactic acid; (2) increased ceramide and adipokines; (3) folic acid. The age-related nature these mechanisms comes from age-associated muscle mass, visceral fat changes in diet. This also explains why many people do not develop disease. Simple lifestyle diet can prevent disease caused by a cascade ev...

Is it really true that simulation models and simulation software should always be regarded as candidates for reuse, or is it better to be selective? What are the obstacles to simulation software and model reuse? Can these be surmounted and, if so, at what cost? There is a range of levels at which simulation software may be reused, a range of costs to be borne and range of benefits that may be a...