Fluid secretion by the salivary glands of the blowfly Calliphora is regulated by 5-hydroxytryptamine (5-HT) (Berridge, 1970, 1972; Berridge & Prince, 1972). The action of 5-HT is apparently mediated by adenosine 3',5'-monophosphate (cyclic AMP) which thus functions as an intracellular 'second messenger' as has been postulated in many other systems (Robison, Butcher & Sutherland, 1968). Exogenou...