newborns’ bacterial infections due to group b streptococcus (gbs) happen in two forms including early-onset disease or late-onset disease. in this paper, we report a case of early-onset gbs infection in a male infant. a 22-year-old primigravid woman delivers a term normal looking male infant. nasal flaring, grunting, and poor feeding presented soon after birth. an empiric treatment with intrave...

Hypospadias is an anomaly of the male urogenital tract which occurs as a result of deficient closure of the urethral groove. Hypospadias is the most commonly seen urogenital anomaly in male neonates, but it is rarely diagnosed during prenatal period. Herein, a severe hypospadias case which was diagnosed by using 2D (two-dimensional) and 3D (three-dimensional) ultrasonography at 28 weeks of preg...

BACKGROUND A German report suggested significantly better outcomes in terms of perineal care, second stage length and neonatal outcome for users of Epi-No. OBJECTIVE To carry out a pilot study of the first use of the Epi-No birth training device in Australia for women having their first baby. STUDY POPULATION AND METHODS Forty-eight primigravidae having their confinement at Birralee Birthin...

Methods A 31-year-old primigravid woman presented with a twin pregnancy at 14 weeks of gestation for evaluation of structural abnormalities in one co-twin. The marriage was non consanguineous. There was not history of genetic disorders or structural anomalies noted in the both parents. This was her first pregnancy and it was achieved by in vitro fertilization (ivf) and embryo transfer. One embr...

Splenic rupture during pregnancy is considered a catastrophic condition associated with high maternal and fetal mortality and morbidity. Herein, we report a case of severe preeclampsia that underwent cesarean delivery with subsequent spontaneous splenic rupture. A 21-year-old primigravid woman was transferred to our center due to severe preeclampsia that underwent cesarean delivery because of u...

A 37-year-old primigravid woman at 35 weeks of pregnancy was seen for a 20-day history of multiple inflammatory skin lesions on her upper chest wall and both breasts. She had a past history of systemic lupus erythematosus (SLE) with active kidney disease, positive antinuclear antibodies at a titer of 1/360, anti-double-stranded DNA, and antiRo, and she was on treatment with prednisone (15 mg/d)...

Aggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggesting a hormonal dependency. We report this rare condition in a 29-year-old primigravid female with a...

Background: Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant condition. It is rarely seen in pregnancy and even more rarely has uterine manifestations. Case: A 29-year-old primigravid woman with HHT was noted to have vascular manifestations of her disease in the lower uterus, distal rectum, pelvis, and bladder before pregnancy. Prior to delivery, a case conference was he...

Malaria infections during pregnancy can lead to the delivery of low-birth-weight infants. In this study, cytokine mRNA was measured in placentas from 23 malaria-infected and 21 uninfected primigravid women who had delivered in Mangochi, Malawi, a region with a high rate of transmission of falciparum malaria. Significantly increased expression of interleukin (IL)-1beta, IL-8, and tumor necrosis ...

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family is a highly polymorphic class of variant surface antigens encoded by var genes that play an important role in malaria pathogenesis. This report describes the unexpected finding that 1 of the var genes encoding a PfEMP1 variant that binds to the host receptor chondroitin sulfate A (CSA) and is implicated in malaria in pregn...