Activation of primary alcohols in the presence KO t Bu/DMF allowed synthesis N -heteroarenes via alkylation C(sp 3 )–H bond methyl azaarenes. A mechanism involving formation an alkyl formate intermediate is proposed.

3. The enzyme system could be concentrated from growth media, though with some loss, by ammonium sulphate precipitation. 4. Of the substances tested, all the primary aromatic alcohols, which included fi-naphthylcarbinol, benzyl alcohol and seven other ringsubstituted benzyl alcohols, were oxidized, but three secondary I-phenylethanols were not. Glucose, ethanol, butanol and the L-amino acids te...

A mild method for the regioselective synthesis of propargyl ethers by the coupling of propargyl alcohols with a range of other alcohols is described. The method employs an air- and moisture-tolerant rhenium-oxo complex ((dppm)ReOCl3) as a catalyst for the formation of sp3-carbon-oxygen bonds without the need for prior activation of the propargyl alcohol or deprotonation of the alcohol nucleophi...

PS-TEMPO, a polymer-supported 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) was successfully applied as a recyclable, active and selective catalyst for the oxidation of alcohols. Bleach, molecular oxygen and air were successfully used as terminal oxidant under conditions suitable for industrial applications. The intrinsic activity and selectivity of TEMPO for primary alcohols to aldehydes were r...

An efficient, general palladium catalyst for C–O bond-forming reactions of secondary and primary alcohols with a range of aryl halides has been developed. Use of a catalyst based on a single bulky biarylphosphine ligand L4 (RockPhos, soon to be commercially available) has expanded this chemistry to allow the transformation of a variety of heteroaryl halides, and for the first time, allows for t...