OBJECTIVE Recommendations that purified protein derivative (PPD) RT-23 tuberculin should not be kept and used more than 24 to 48 hours after opening are rarely complied with. The aim of this study was to determine whether using PPD RT-23 tuberculin from vials that had been open for a longer time could affect results of tuberculin tests and whether the solution could become contaminated. METHO...

The value of tuberculin skin testing in the diagnosis of active tuberculosis remains uncertain. Interpretation of tuberculin tests would be easier if the tuberculin test profiles in different communities were accurately known. We reviewed 468 Mantoux test reactions in patients coming to Hospital Universiti Sains Malaysia with suspected tuberculosis. Eighty six percent of patients with active tu...

It is well known that after Bacille Calmette-Gue'rin (B.C.G.) vaccination the degree of allergy as shown by the tuberculin test is of a lesser order than that after infection with virulent tubercle bacilli. For this reason it may be necessary to perform several successively stronger tuberculin tests up to 100 units of old tuberculin (Mantoux 1/100) before a positive post-vaccination test is obt...

SUMMARY Tuberculoma of the central nervous system is one of the rare and unusual form of Tuberculous in Iranian children, that often present with mass lesion. This is report A 14 months old boy, admitted because ahd fever, irritability, anorexics had right side hemiplegia for two months. Positive finding was tuberculin test and CT brain scan with 2 hyperdenc mass (Ring Shaped) in the posto-m...

Two independent sets of observations made at the Devonshire Royal Hospital have both suggested that tuberculin sensitiveness in cases of spondylitis ankylopoietica tends to excess. The phenomenon has been noted recently during von Pirquet testing of assorted rheumatic patients, and formerly' as part of a study of the disease itself. Moreover, such patients have sometimes been treated by vaccina...

Interferon-gamma release assays for the diagnosis of tuberculosis (TB) can give indeterminate results. The prevalence of indeterminate test results (ITRs) among T-SPOT.TB tests was assessed. A retrospective analysis of samples processed in 2005 was performed. ITRs were assessed by age, sex, immunosuppression, distance to the laboratory and season. A subgroup of tests performed for specific indi...

One hundred and two patients with inoperable bronchial carcinoma who had tuberculin tests at the time of diagnosis were followed up to see if there was any correlation between their degree of tuberculin reactivity and their subsequent survival time. There was a significant difference in survival between positive and negative tuberculin reactors (Log Rank Test P less than 0.05), the former havin...