Objective: The aim of this study was to investigate causal association of serum ferritin with pre-term labour. Materials and Methods: This is a case-control study done on one hundred and twenty women from July 2005 to June 2007 in the department of obstetrics and gynecology of Bangabandhu Sheikh Mujib Medical University (BSMMU) and Mother and Child Health Training Institute (MCHTI), Azimpur, Dh...

Prostaglandins, pro-inflammatory cytokines, extracellular matrix remodelling enzymes and nuclear factor-kappa B (NF-κB) are involved in the mechanisms of term and preterm parturition. Recent studies have reported an increase in angiogenesis-related genes during term and preterm labour, including placental growth factor (PLGF). In non-gestational tissues, PLGF induces inflammation via NF-κB. The...

Cyclic nucleotide phosphodiesterases (PDE) are the enzymes catalyzing the hydrolysis and inactivation of the second messengers, cAMP and cGMP. Eleven PDE families are described to date, and selective inhibitors of some PDEs families are currently used in clinic for treating cardiovascular disorders, erectile dysfunction, and pulmonary hypertension. Isoforms of the PDE4 family are involved in sm...

Background: Preterm labor and delivery are very challenging obstetric complications encountered by obstetrician as preterm births the major cause of perinatal neonatal morbidity mortality.Methods: An observational study was conducted in Department Obstetrics Gynaecology, Himalayan Institute Medical Sciences (HIMS), Jollygrant, Dehradun, over a period one year which 105 pregnant were observed ri...

Objective: The purpose of this study is to determine the association vaginal infection in preterm deliveries. Study Design: Retrospective/prospective Place and Duration: Gynaecology Obstetrics department MSF Women’s Hospital Peshawar King Abdullah Teaching Hospital, Mansehra for duration six months form August 2021 January 2022. Methods: Total 76 females with ages 18-(42) years were presented s...