BACKGROUND The best and most cost-effective bowel cleansing regimen for patients undergoing flexible sigmoidoscopy is not known. The aim of this study was to compare patient tolerance, quality of preparation, and cost of 2 bowel cleansing regimens for flexible sigmoidoscopy. METHODS Two hundred fifty consecutive patients referred for screening flexible sigmoidoscopy were randomized to receive...

The aim of this study was to evaluate the immediate changes in the pulp-dentin complex that result from crown preparation, and their correlation with the thickness of remaining dentin and the preparation technique (with or without water spray cooling). Thirty upper intact premolars scheduled for extraction for orthodontic reasons were high speed prepared, extracted immediately after preparation...

BACKGROUND The tremendous output of massive parallel sequencing technologies requires automated robust and scalable sample preparation methods to fully exploit the new sequence capacity. METHODOLOGY In this study, a method for automated library preparation of RNA prior to massively parallel sequencing is presented. The automated protocol uses precipitation onto carboxylic acid paramagnetic be...

For most sample types, the automation of RNA and DNA sample preparation workflows enables high throughput next-generation sequencing (NGS) library preparation. Greater adoption of small RNA (sRNA) sequencing has been hindered by high sample input requirements and inherent ligation side products formed during library preparation. These side products, known as adapter dimer, are very similar in s...

OBJECTIVES The Residency Review Committee training requirements for emergency medicine residents (EM) are defined by consensus panels, with specific topics abstracted from lists of patient complaints and diagnostic codes. The relevance of specific curricular topics to actual practice has not been studied. We compared residency graduates' self-assessed preparation during training to importance i...

Background and study aims: Previous studies have reported that diabetes mellitus is an independent risk factor for inadequate bowel preparation. Current guidelines do not recommend a specific preparation for this patient population. The aims of this study were to assess the efficacy, safety, and tolerability of an adapted preparation protocol for colon cleansing in patients with type 2 diabetes...

Kinetic parameters of the ammonolysis reaction of dichloroethane in nonaqueous media are studied and the optimum reaction conditions are reported. A suitable reactor for running the reaction under high pressure in the range of 50 to 500 °C is designed. Kinetic behaviours of the system is studied and other reaction parameters such as rate constant, kinetic order, and activation energy are de...

In this study the uptake and metabolism of adenosine by mitochondria has been investigated. Incubation of CEM cells mitochondria preparation with [3H] -adenosine showed substantial uptake and metabolism of adenosine. Adenosine was both anabolized to AMP, ADP and ATP, and also catabolized to inosine. The highest concentration of metabolites in extracted mitochondria was due to AMP. The mito...

jobs and become 'unemployable'. There is in fact practically no provision for these two groups, and some of the latter group may end up in a hospital for the subnormal. Research carried out in the Industrial Training Units at the Manor Hospital, Epsom, has shown that given training, these patients can develop skills and assets that at first seemed non-existent, and that personality problems can...

All Bell experiments carried out so far have had ten or more times fewer coincidence counts than singles counts and this, in effect, means a detection efficiency under 10%. Therefore, all these experiments relied only on coincidence counts and herewith on additional assumptions. Recently, however, Santos devised hidden variable models which do not obey the assumptions and thus made the experime...