نتایج جستجو برای: prenatal stress

تعداد نتایج: 473229  

Journal: :Neuroscience and biobehavioral reviews 2015
Olena Babenko Igor Kovalchuk Gerlinde A S Metz

Research efforts during the past decades have provided intriguing evidence suggesting that stressful experiences during pregnancy exert long-term consequences on the future mental wellbeing of both the mother and her baby. Recent human epidemiological and animal studies indicate that stressful experiences in utero or during early life may increase the risk of neurological and psychiatric disord...

Journal: :Early human development 2002
E J H Mulder P G Robles de Medina A C Huizink B R H Van den Bergh J K Buitelaar G H A Visser

BACKGROUND Animal experiments have convincingly demonstrated that prenatal maternal stress affects pregnancy outcome and results in early programming of brain functions with permanent changes in neuroendocrine regulation and behaviour in offspring. AIM To evaluate the existing evidence of comparable effects of prenatal stress on human pregnancy and child development. STUDY DESIGN Data sourc...

2017
Nombuso Valencia Pearl Mkhize Lihle Qulu Musa Vuyisile Mabandla

Febrile seizures are childhood convulsions resulting from an infection that leads to an inflammatory response and subsequent convulsions. Prenatal stress has been shown to heighten the progression and intensity of febrile seizures. Current medications are costly and have adverse effects associated with prolonged use. Quercetin flavonoid exhibits anti-inflammatory, anti-convulsant, and anti-stre...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2006
Korami Dembele Xing-Hai Yao Li Chen B L Grégoire Nyomba

Prenatal ethanol (EtOH) exposure is associated with low birth weight, followed by increased appetite, catch-up growth, insulin resistance, and impaired glucose tolerance in the rat offspring. Because EtOH can induce oxidative stress, which is a putative mechanism of insulin resistance, and because of the central role of the hypothalamus in the regulation of energy homeostasis and insulin action...

2016
Saskia Trump Matthias Bieg Zuguang Gu Loreen Thürmann Tobias Bauer Mario Bauer Naveed Ishaque Stefan Röder Lei Gu Gunda Herberth Christian Lawerenz Michael Borte Matthias Schlesner Christoph Plass Nicolle Diessl Markus Eszlinger Oliver Mücke Horst-Dietrich Elvers Dirk K. Wissenbach Martin von Bergen Carl Herrmann Dieter Weichenhan Rosalind J. Wright Irina Lehmann Roland Eils

Psychological stress during pregnancy increases the risk of childhood wheeze and asthma. However, the transmitting mechanisms remain largely unknown. Since epigenetic alterations have emerged as a link between perturbations in the prenatal environment and an increased disease risk we used whole genome bisulfite sequencing (WGBS) to analyze changes in DNA methylation in mothers and their childre...

Journal: :Journal of Korean medical science 2016
Soo-Young Bhang Eunhee Ha Hyesook Park Mina Ha Yun-Chul Hong Boong-Nyun Kim Soo-Jeong Lee Kyung Yeon Lee Ja Hyeong Kim Joseph Jeong Kyoung Sook Jeong Boeun Lee Yangho Kim

Our objective is to evaluate the relationships between prenatal maternal stress and depressive symptoms, respectively, and infant neurodevelopment at 6 months, adjusted for heavy metals and oxidative stress. This research is a part of a multi-center birth cohort study in South Korea. Information on stress and depressive symptoms was collected during the first trimester using Psychosocial Well-B...

Journal: :Psychoneuroendocrinology 2013
Carolina de Weerth Jan K. Buitelaar Roseriet Beijers

INTRODUCTION Our aim was to examine infants' behavioral and physiological stress responses to three weekly maternal separations, in relation to maternal prenatal psychosocial stress and cortisol. The hypothesis was that more prenatal stress and higher cortisol concentrations would predict smaller decreases in negative behavior and cortisol responses over the separations (i.e. less habituation)....

2008
Brooks B. Gump Paul Stewart Jacki Reihman Ed Lonky Tom Darvill Patrick J. Parsons Douglas A. Granger

BACKGROUND A few recent studies have demonstrated heightened hypothalamic-pituitary-adrenal (HPA) axis reactivity to acute stress in animals exposed to heavy metal contaminants, particularly lead. However, Pb-induced dysregulation of the HPA axis has not yet been studied in humans. OBJECTIVE In this study, we examined children's cortisol response to acute stress (the glucocorticoid product of...

Journal: :Psychoneuroendocrinology 2021

The COVID-19 pandemic represents a collective trauma that may have enduring stress effects during sensitive periods, such as pregnancy. Prenatal result in epigenetic signatures of stress-related genes (e.g., the serotonin transporter gene, SLC6A4) turn influence infants’ behavioral development. In April 2020, we launched longitudinal cohort study to assess and vestiges COVID-19-related prenatal...

Journal: :Neuro endocrinology letters 2014
Jun-Ming Fan Xue-Qun Chen Ji-Zeng Du

Prenatal stress (PNS) is associated with increased biological risk for mental disorders such as anxiety and depression later in life, and stress appear to be additive to the PNS influences. Among the most widely cited and accepted alternative hypotheses of anxiety and depression is dysfunction of the HPA axis, a system that is central in orchestrating the stress response. Therefore, understandi...

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