PURPOSE Antenatal hydronephrosis (AH) is found in 0.5%-1% of neonates. The aim of the study was to assess the urinary concentrations of 3 biomarkers, endothelin-1 (ET-1), monocyte chemotactic peptide-1 (MCP-1), and N-acetyl-glucosaminidase (NAG) in severely hydronephrotic neonates. MATERIALS AND METHODS Neonates with a history of prenatal hydronephrosis were enrolled in the prospective study ...

BACKGROUND Prenatal hydronephrosis (PNH) is dilation in urinary collecting system and is the most frequent neonatal urinary tract abnormality with an incidence of 1% to 5% of all pregnancies. PNH is defined as anteroposterior diameter (APD) of renal pelvis ≥ 4 mm at gestational age (GA) of < 33 weeks and APD ≥ 7 mm at GA of ≥ 33 weeks to 2 months after birth. All patients need to be evaluated a...

Abstract Aim Ureterosciatic hernia (USH) is an extremely unusual condition, with presentations ranging from asymptomatic, to flank pain, renal failure, septic shock and even obstructive uropathy. Due its rarity, there are no recommendations on the treatment of USH. We therefore carried out a systemic review published literature management. Method The was completed using three search terms: “ure...

The present study evaluated the prognostic value of three-dimensional ultrasound for fetal hydronephrosis. Pregnant females with fetal hydronephrosis were enrolled and a novel three-dimensional ultrasound indicator, renal parenchymal volume/kidney volume, was introduced to predict the postnatal prognosis of fetal hydronephrosis in comparison with commonly used ultrasound indicators. All ultraso...

The authors of “Mini incision open pyeloplasty Improvement in patient outcome” are to be congratulated for publishing their work in the era of minimally invasive surgery (MIS) (1). Refinement of open surgery should still be ongoing and published because not every surgeon can do MIS, and not every patient can afford MIS which is more expensive than that of open surgery. However, two issues need ...

BACKGROUND Urinary tract obstruction and postoperative hydronephrosis are risk factor for renal function deterioration after orthotopic ileal neobladder construction. However, reports of relationship between transient hydronephrosis and renal function are limited. We assess the influence of postoperative transient hydronephrosis on renal function in patients with orthotopic ileal neobladder con...

INTRODUCTION Dilation of urinary tract occurs without the presence of obstruction. Diagnostic methods that depend on renal function may elicit mistaken diagnosis. Whitaker (1973) proposed the evaluation of urinary tract pressure submitted to constant flow. Other investigators proposed perfusion of renal pelvis under controlled pressure, making the method more physiological and reproducible. The...

Congenital progressive hydronephrosis (cph) is a spontaneous recessive mutation that causes severe hydronephrosis and obstructive nephropathy in affected mice. The mutation has been mapped to the distal end of mouse chromosome 15, but the mutated gene has not been found. Here, we describe the identification of a single base pair change in aquaporin-2 (Aqp2) in cph mutants through genetic linkag...

Hydronephrosis means dilation of the pelvis of the kidney by urine which has accumulated, because of obstruction of the urinary tract at some point distal to the pelvis, most commonly the pelvi-ureteral junction. If the obstruction be at a lower level, the ureter becomes dilated first, and the kidney is involved later. Occasionally the obstruction is confined to one or more of the minor calyces...