When faced with a preterm delivery of an extremely premature neonate between 22-24 weeks (EPRN), doctors are confronted by a three-fold uncertainty of age, viability and prognosis that influence their decision whether or not to resuscitate the neonate. Firstly, in the delivery room the preterm neonate’s age is seldom precisely known, and successful resuscitation depends on the neonate’s accurat...

  Background :Severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. This study was conducted to investigate the causes of severe hyperbilirubinemia leading to Exchange Transfusion (ET) from March 2009 to March 2011 in Bahrami children hospital, Tehran, Iran in order to establish guidelines to prevent profound jaundice & ET.   Methods : 94 neonates underwent ...

Perforated NEC in the fragile, premature infant remains a complex neonatal and surgical problem. Future investigation into the basic mechanisms of the intestinal inflammatory response in the premature neonate may allow for preventive strategies in the management of NEC. Until then, surgical management for perforated NEC will remain a necessary intervention to treat the complications of this dis...

Pulmonary interstitial emphysema (PIE) is not an uncommon finding in premature infants with respiratory distress who need respiratory support by mechanical ventilation. PIE has been reported in a few cases of neonates in whom either no treatment other than room air was given or they were given continuous positive end-expiratory pressure (CPAP) support. We present a case of a premature neonate w...

Background. The outcome of neonates with congenital cutaneous Langerhans cell histiocytosis (LCH) is variable. Observations. We report a case of LCH in a female premature neonate born at 33-week gestation. She had disseminated cutaneous lesions, which consisted of hemorrhagic papules and vesicles, with sparse healthy skin areas, and the hands and feet were contracted with scarring and blackened...

Introduction: Improvements in newborn intensive care led to decreased mortality, but increased the morbidity rates of preterm infants. This study have designed to evaluate the short- term outcome in premature infants admitted to NICU at Amirkola Children Hospital(ACH) , northern Iran from Mar20,2010- Mar21,2011 Methods: All the premature infants admitted to NICU and newborn services from Mar20...

INTRODUCTION Music stimulation has been shown to provide significant benefits to preterm infants. Thus the aim of this study was determine the effect of recorded mum's lullaby and Brahm's lullaby on oxygen saturation in preterm infants. METHODS This double-blind randomized controlled trial was carried out on 66 premature newborns with the postnatal age of ≥3 days and weight ≤ 2800 grams at Ta...

AIMS To determine the level of oxidative stress and cell damage as a result of exposure to O(2) at birth. METHODS Using glutathione S transferase (GST) as an indicator of oxidative stress, GST activity in cord blood was compared with that in samples taken three hours after birth. Twenty four prematurely born infants and eight full term infants were studied. To test whether stronger effects oc...

Hypoxic/ischemic (HI) brain injury in newborn full-term and premature infants is a common and pervasive source of life time disabilities in cognitive and locomotor function. In the adult, HI induces glutamate release and excitotoxic cell death dependent on NMDA receptor activation. In animal models of the premature human infant, glutamate is also released following HI, but neurons are largely i...