BACKGROUND During pregnancy, patients with rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) can experience active disease, which might be influenced by adjustment of treatment around conception. The aim of this study was to identify possible risk factors of disease flares during pregnancy and to evaluate the effect of treatment in pregnant patients experiencing a flare. METHODS P...

Choriocarcinoma and placental site trophoblastic tumor (PSTT) are rare varieties of gestational trophoblastic disease (GTD). PSTT alone constitutes about 1-2% of all trophoblastic tumors, which presents at early reproductive age and the serum beta-hCG level is much lower than choriocarcinoma. This tumor usually invades the myometrium and its depth of penetration is a prognostic factor. The firs...

Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed by a variety of cells and tissues such as macrophages, dendritic cells, cells of the endocrine system and by the placenta. IFN- γ is the main inducer of this enzyme. IDO acts as an important defense mechanism of innate immunity against pathogens. It also has tumor suppressive activity and prolong...

Background Desmoid tumors are benign soft tissue tumors that locally invade adjacent tissue. There is a paucity of reports describing the rapid growth of these tumors during pregnancy. Case A giant desmoid tumor arising from the left abdominal wall of a young female patient with rapid growth during pregnancy is described. Preoperative evaluation included ultrasonography and magnetic resonance i...

conclusions pc-rplnd is one the major operations in the field of urology, which is associated with significant adjunctive surgeries. in appropriate cases, pc-rplnd was associated with good cancer specific survival in tertiary oncology center. results twenty-one patients underwent bilateral pc-rplnd. mean age was 26.3 years (ranged 16 - 47). mean size of retroperitoneal mass after chemotherapy w...

Introduction:. Infantile hemangioma is a prevalent tumor in children Method: This research case control study. The data from January 1, 2019 to December 31, 2021 were processed and presented assess the incidence percentage of risk factors for infantile hemangioma. Univariate, bivariate multivariate analysis was performed using Microsoft Excel SPSS 21 spreadsheet program. Result : Total sample t...