Nitrite and nitrate are main stable products of nitric oxide, a pivotal cellular signaling molecule, in biological fluids. Therefore, accurate measurement of the two ions is profoundly important. Nitrite is difficult to be determined for a larger number of interferences and unstable in the presence of oxygen. In this paper, a simple, cost-effective and accurate HPLC method for the determination...

The action of buffered potassium permanganate as a fixative for electron microscopy has been investigated. Electron contrast has been shown to be produced by the deposition of granular material in the tissue. The particles are about 50 A in diameter. Actual fixation of the tissue is performed by the dehydrating alcohol. Histochemical studies have shown that RNA and histones are removed, whereas...

To the Editor, The Indian Medical Gazette. Sir,?In the issue of the Gazette for April 1926, on p, 178, is reported a case of recovery from cobra poisoning in which potassium permanganate crystals were used locally in the incisions made at the bitten parts with resultant sloughing, and it is in this connection that I write to enquire whether the rubbing in of these crystals is of any real value ...

Epoxy resin appears to be the best embedding material for preserving tissues for electron micros-copy. Its low linear coefficient of contraction I ensures that no appreciable distortion can occur owing to polymerization damage or excessive shrinkage (1). This plastic also is exceptionally stable in the electron beam, so that surface damage to the section is slight. Although Araldite blocks are ...

A new chemiluminescence method using flow injection is described for the determination of four penicillins, namely: phenoxymethylpenicillin potassium, amoxicillin, ampicillin, and ampicillin sodium. The method is based on sensitizing effect of these drugs on the chemiluminescence reaction of potassium permanganate in sulfuric acid with glyoxal. The different experimental parameters affecting th...