Electrical synapses (gap junctions) play a pivotal role in the synchronization of neuronal ensembles which also makes them likely agonists of pathological brain activity. Although large body of experimental data and theoretical considerations indicate that coupling neurons by electrical synapses promotes synchronous activity (and thus is potentially epileptogenic), some recent evidence question...

PURPOSE To assess the clinical significance of temporal pole abnormalities (temporopolar blurring, TB, and temporopolar atrophy, TA) in patients with temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS) with a long post-surgical follow-up. METHODS We studied 60 consecutive patients with TLE-HS and 1.5 preoperative MRI scans who underwent surgery and were followed up for at least 5 year...

Introduction The post-operative period is characterised by increased IL-6 production and clinical features of immune suppression. In vitro anti-inflammatory actions of IL-6 are mediated through suppression of interferon gamma (IFNg) [1]. The clinical significance of IL-6 in mediating post-operative immune suppression remains unclear. Objectives To evaluate the role of IL-6 pathways in post-oper...

Let g ∈ Q be not −1 or a square. Let Pg denote the set of primes p such that g is a primitive root mod p. Let 1 ≤ a ≤ f, (a, f) = 1. Under the Generalized Riemann Hypothesis (GRH) it can be shown that the set of primes p ∈ Pg with p ≡ a(mod f) has a natural density. In this note this density is explicitly evaluated. This generalizes a classical result of Hooley.

The dynamical characteristics of a complex system can be inferred from an observation of the system. In this paper, a calculation algorithm of the damping time of a signal from a complex system is presented by using information retrieve and autoregressive model. Two EEG recordings during tonic–clonic seizure are analyzed; the damping time of EEG calculated by means of the proposed algorithm can...

although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure duration remain remains to be determined. in the present study, we examined the role of nmda (n-methyl-d-aspartate), non-nmda and estrogenic receptors in estradiol benzoate ...

patients and methods the study adopts a quasi-experimental research design. a total of 102 mothers of children presenting with febrile seizure and admitted to a teaching hospital in iran were equally assigned to three groups: group i received no intervention (control group), group ii received a febrile seizure information pamphlet, and group iii received the febrile seizure information pamphlet...

Defining a bio-electrical marker for the brain area responsible for initiating a seizure remains an unsolved problem. Fast gamma activity has been identified as the most specific marker for seizure onset, but conflicting results have been reported. In this study, we describe an alternative marker, based on an objective description of interictal to ictal transition, with the aim of identifying a...

A patient with remote cerebellar hemorrhage (RCH) who was presented at the authors' hospital with seizure and delayed emergence from anesthesia after loss of cerebrospinal fluid (CSF) through a dural tear during lumbar spine surgery is described. RCH is a rare and unpredictable complication after spinal surgery. Its most common clinical features are diminished consciousness, headache, and seizu...