Background Hematoporphyrin monomethyl Ether-mediated photodynamic therapy (HMME-PDT) is an effective and safe treatment option for patients with port-wine stain (PWS) might be alternative approach treating PWS. The data of long-term follow-up HMME-mediated PDT are limited. Objective We aimed to evaluate the current skin lesions who underwent HMME-PDT 10 years ago, compare pre post response that...

This article aims to provide a concise overview of the existing literature on Sturge-Weber syndrome in infants. comprehensive review presents key information regarding prevalence, clinical characteristics, diagnostic methods, and available treatments based recent global research. is rare congenital neurocutaneous disorder, affecting approximately 1 20,000 50,000 new-born, caused by somatic muta...

Klippel Trenaunay syndrome refers to a rare congenital anomaly which is characterized by capillary malformation, venous malformation and sometimes lymphatic malformation associated with overgrowth of a limb, with soft tissue hypertrophy and/or bony hypertrophy. The anomaly, if present, is present at birth and usually involves the lower limbs as well as portion of trunk, face, uppper limb or hea...

Cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during pulsed laser treatment of port wine stain (PWS) birthmarks. Unfortunately, the current approach to CSC does not provide the necessary epidermal protection for all patients, particularly those with darker skin types. Therefore, alternative approaches need to be sought to improve PWS laser therapy. On a previous n...

Sturge-Weber syndrome was diagnosed in a neonate on basis of a characteristic port-wine stain. In the absence of any acute neurologic episode, MR images obtained when the infant was aged 3 months showed a typical pial vascular dysplasia, as well as prominent hypotrophy of the homolateral hemisphere. Areas suggesting the presence of developmental dysplasia of the cerebral mantel were found in as...

 Hepatocellular adenomas (HCAs) are benign liver tumors recently characterized into 4 different types according to genetic, pathological and clinical features. The prognosis is not well established yet and malignant transformation has been recently associated with β-catenin activation. We aimed to describe a case of a pigmented HCA with β-catenin nuclear expression and inflammatory features and...

A 49-year-old farmer presented with papules on the face, arms, chest and back associated with sclerosis. Histopathology and PAS stain confirmed the clinical diagnosis of scleromyxedema. He also had elevated CPK levels due to myopathy. Screening for internal malignancy was negative.