Many properties of porous calcium phosphate ceramics have been described, but how pore size influences bony integration of various porous ceramics remains unclear. This study was performed to quantify the bony ingrowth and biodegradability of two porous calcium phosphate ceramics with four different pore size ranges (45-80 microm, 80-140 microm, 140-200 microm, and 200-250 microm). Hydroxyapati...

Next-generation synthetic bone graft therapies will most likely be composed of resorbable polymers in combination with bioactive components. In this article, we continue our exploration of E1001(1k), a tyrosine-derived polycarbonate, as an orthopedic implant material. Specifically, we use E1001(1k), which is degradable, nontoxic, and osteoconductive, to fabricate porous bone regeneration scaffo...

Magnesium is a biocompatible and biodegradable metal which possesses suitable mechanical properties for load-bearing applications in orthopaedics. Moreover, magnesium ions, the products of magnesium corrosion, improve growth of the new bone tissue. Implementation of the porosity into these materials compromises values of mechanical properties closer to the values of nature bone and allows the i...

peri-implantitis is a site-specifi c infectious disease that causes an infl ammatory process in soft tissues, and bone loss around an osseointegrated implant in function. the etiology of the implant infection is conditioned by the status of the tissue surrounding the implant, implant design, degree of roughness, external morphology, and excessive mechanical load. the microorganisms most commonl...

in this study, hydroxyapatite was coated on titanium substrates by plasma spraying process. a well-known porous and lamellar microstructure was found in the lateral and outer surface of coating. the phase composition was studied by xrd and the morphological and the microstructural aspects were investigated by scanning electron and optical microscopy. the hardness of coatings and substrates was ...

Metals with certain porosity are a new class of materials extremely low density and unique combination excellent mechanical, thermal, electrical, biocompatible properties. Absorption impact shock energy, dust fluid filtration, construction materials, most importantly, implants all potential applications for metallic foams. An orthopaedic implant made foam can provide an open-cell structure that...

Porous β-tricalcium phosphate (TCP) displays osteoinductivity in certain animals in the absence of osteoinductive agents. We evaluated whether the microstructure may be an important determinant of osteoinduction, and also investigated how bone formation was promoted using β-TCP combined with bone marrow aspirates. We prepared two types of β-TCP, namely, β-TCP A, which possessed interconnected m...

Titanium is widely used as a bone implant material due to its biocompatibility and high resilience. Since its Young's modulus differs from bone tissue, the resulting "stress shielding" could lead to scaffold loosening. However, by using a scaffold-shaped geometry, the Young's modulus can be adjusted. Also, a porous geometry enables vascularisation and bone ingrowth inside the implant itself. Ad...

BACKGROUND Maxillofacial defects caused by cancer treatment are a huge problem affecting the quality of life of patients. Some of these deformities are minimized using facial epitheses, which need some additional retention devices like glasses or skin adhesives. The use of extraoral fixtures as bone anchorage was introduced many years ago and since then many patients were rehabilitated with bet...