A 65-year-old man presented with an asymptomatic lesion on the left parietal scalp of 6 months’ duration. Three years prior, a cylindroma on the same area was excised by a general surgeon. Physical examination revealed a solitary 6 mm salmon-pink, firm, dome-shaped papule on the left parietal scalp (Figure 1). Dermatoscopic evaluation showed arborizing telangiectasia and several scattered white...

Spiradenoma & cylindroma are relatively uncommon sweat gland tumors. These lesions along with trichoepithelioma can co-exist and this gives support to the theory that they are part of the same spectrum and have a similar derivation.They can occur as separate lesions or within a single tumor mass as collision tumors.Here we report a case of a 67 year old female who presented with multiple papulo...

BACKGROUND Atypical lentiginous nevus (of the elderly) is a peculiar form of dysplastic nevus. Clinically, this condition can resemble malignant melanoma and histologically, it has a lentiginous pattern with variable degrees of atypia and an absence of dermal nests. These features may lead to an erroneous diagnosis of lentigo maligna melanoma or lentiginous melanoma. MATERIAL AND METHODS We r...

A previous in vitro study revealed that Wilms's tumor 1 (WT-1) transcripts were detectable in 7 of 9 melanoma cell lines, but not in any of 5-normal melanocyte strains tested. Our current study assessed the expression levels of WT-1 protein in clinical samples, to determine whether the expression levels of the WT-1 protein may be used as a novel marker to assist differential diagnosis. Paraffin...

A 65-year-old male presented with a slowly enlarging nodule on his right leg, which had been present for 10 years and which had gradually increased in size over the previous 6 months. Physical examination revealed a red and dark bluish, dome-shaped nodule, 26 mm × 22 mm in size, on the right side of the posterior aspect of his right leg (Fig. 1). Histopathology revealed a well-demarcated, solid...

Adenoid cystic carcinoma (ACC), is one of the most common primary malignant tumors of the lacrimal gland. It accounts for less than 4% of all lacrimal gland tumours. Mean age of incidence is 40 years 1 . It has a poor prognosis, in view of its locally invasive and metastatic potential .2-7 . Radical Excision with negative margin is the treatment of choice. However, the complex anatomy of orbita...

A 74-year-old woman was referred for evaluation and treatment of a tumor measuring 3 x 2 cm in the left preauricular region that has been progressively growing in the past years. Physical examination revealed an hemispheric and firm tumor with reddish coloration and telangiectases. The patient has been using a wig during the past 15 years to cover the scalp lesions. The patient underwent comple...

Blue nevi are dermal dendritic melanocytic proliferations presenting as papules, nodules or plaques of blue, blue-gray or blue-brown color. Dermoscopic appearance commonly shows global patterns as homogeneous mono/dichromatic pigmentation and multichromatic pigmentation. Here, we report the case of a blue nevus with the dermoscopic feature of peripheral streaks with branches. With histopatholog...

BACKGROUND AND OBJECTIVE Acquired dermal melanocytosis (ADM; acquired bilateral nevus of Ota-like macules) is known for its recalcitrance compared with Nevus of Ota, and we assume that one of the reasons is a higher rate and degree of postinflammatory hyperpigmentation (PIH) seen after laser treatments. METHODS Topical bleaching treatment with 0.1% tretinoin aqueous gel and 5% hydroquinone oi...