The cell is a mechanical machine, and continuum mechanics of the fluid cytoplasm and the viscoelastic deforming cytoskeleton play key roles in cell physiology.We reviewmathematicalmodels of intracellular fluidmechanics, from cytoplasmic fluid flows, to the flow of a viscous active cytoskeletal gel, to models of two-phase poroviscous flows, to poroelastic models. We discuss application of these ...

Low back pain is a clinical and public health problem affecting more than half of the population. Disc degeneration is a major source of low back pain. Long-term exposure to whole body vibration or sedentary work postures may have high association with disc degeneration. It is hypothesized that there is a preferential frequency for vibrational loading, which may increase the efficiency for flui...

PURPOSE This paper addresses the diagnostic idea proposed in [11] to measure the parameter called rate of creep of axillary fold of tissue using modified Harpenden skinfold caliper in order to distinguish normal and edematous tissue. Our simulations are intended to help understanding the creep phenomenon and creep rate parameter as a sensitive indicator of edema existence. The parametric analys...

[1] Thirty interferometric synthetic aperture radar (InSAR) images, spanning various intervals during 1992–2000, document coeruptive and posteruptive deformation of the 1992–1993 eruption on Seguam Island, Alaska. A procedure that combines standard damped least squares inverse methods and collective surfaces, identifies three dominant amorphous clusters of deformation point sources. Predictions...

This paper presents a new approach to study the effects of temperature on the poroelastic and viscoelastic behavior of articular cartilage. Biphasic solid-fluid mixture theory is applied to study the poro-mechancial behavior of articular cartilage in a fully saturated state. The balance of linear momentum, mass, and energy are considered to describe deformation of the solid skeleton, pore fluid...

A better understanding of fluid-related processes such as poroelastic rebound of the upper crust and weakening of the lower crust beneath the volcanic arc helps better understand and correctly interpret the heterogeneity of postseismic deformation following great subduction zone earthquakes. The postseismic deformation following the 2011 Mw9.0 Tohoku earthquake, recorded with unprecedented high...

Modelling the course of healing of a long bone subjected to loading has been the subject of several investigations. These have succeeded in predicting the differentiation of tissues in the callus in response to a static mechanical load and the diffusion of biological factors. In this paper an approach is presented which includes both mechanoregulation of tissue differentiation and the diffusion...

In this work we develop a high-resolution mapped-grid finite volume method code to model wave propagation in two dimensions in systems of multiple orthotropic poroelastic media and/or fluids, with curved interfaces between different media. We use a unified formulation to simplify modeling of the various interface conditions — open pores, imperfect hydraulic contact, or sealed pores — that may e...

Torsion of elastic and poroelastic circular shaft of radially inhomogeneous, cylindrically orthotropic materials is studied with emphasis on the end effects example for extruder. To examine the conjecture of Saint-Venant’s torsion, we consider torsion of circular shaft with one end fixed and the other end free on which tractions that results in a pure torque are prescribed arbitrarily over the fr...