Mitochondrial dysfunction caused by excessive Ca2+ accumulation is a major contributor to cardiac cell and tissue damage during myocardial infarction and ischemia-reperfusion injury (IRI). At the molecular level, mitochondrial dysfunction is induced by Ca2+-dependent opening of the mitochondrial permeability transition pore (mPTP) in the inner mitochondrial membrane, which leads to the dissipat...

A 58-year-old man was referred for resection of a pedunculated polyp, which had a head measuring 3.5×2.8cm and a stalk 1.5cm in diameter, over the sigmoid colon. We initially applied a detachable loop over the stalk, but no total cyanotic change of the polyp head was observed. We applied a second loop, but it became entrapped in the head of the polyp without tightening (●" Fig.1). We attempted ...

In this paper we present a novel polyp region segmentation method for colonoscopy videos. Our method uses valley information associated to polyp boundaries in order to provide an initial segmentation. This first segmentation is refined to eliminate boundary discontinuities caused by image artifacts or other elements of the scene. Experimental results over a publicly annotated database show that...

BACKGROUND Sulindac, a non-steroidal anti-inflammatory drug, causes regression of colorectal adenomas in patients with familial adenomatous polyposis (FAP) but the response is variable. Specific clinical factors predictive of sulindac induced regression have not been studied. METHODS 22 patients with FAP were given sulindac 150 mg orally twice a day. Polyp number and size were determined befo...

BACKGROUND An endometrial polyp is a frequently encountered gynecologic disease with abnormal uterine bleeding and infertility being the two common presenting problems, and hysteroscopic polypectomy is an effective method to remove them. The postoperative polyp recurrence might result in reappearance of abnormal uterine bleeding or infertility, whereas factors influencing the postoperative recu...

Polyphosphate (polyP) is an abundant and physiologically important biomolecule for virtually any living cell. Therefore, determination of changes in cellular content of polyP is crucial for its functional characterization. Determination of cellular polyP has been performed by many different methods, and the lack of a standardized procedure is possibly responsible for the large dispersion of res...

Fibrovascular polyps of the esophagus and hypopharynx are benign tumors of the upper digestive tract. The majority of these polyps are located in the upper part of the esophagus but the hypopharyngeal fibrovascular polyps are only rarely seen. Most of them are surgically treated and this is usually done through a cervical incision, although some of them have been removed endoscopically. The aut...

fibrovascular polyps are rare, pedunculated, tumor-like lesions that are usually found in the esophagus; occurrence in the stomach is very rare. to our knowledge, sonographic and ct findings of a fibrovascular polyp in the stomach have never been reported. here, we report a case of a fibrovascular polyp that was identified in the gastric antrum and prolapsed into the duodenal bulb. sonography r...

conclusion we constructed and validated a ct colonography phantom with correct density allowing performance of reproducible experiments. materials and methods we found 15 different phantom designs by literature search and compared their advantages and disadvantages based on their description and images. we tested various materials for density and mechanical properties and constructed a phantom ...

Polypectomy-snare entrapment is a rare but serious complication of colonoscopy, frequently requiring surgical intervention. We report a case of polypectomysnare entrapment successfully treated using a novel endoscopic “zip-line” approach that, to our knowledge, has not been previously reported. A 35-year-old woman underwent a colonoscopy in our office-endoscopy suite, during which a 4 cm, broad...