نتایج جستجو برای: polymersomes

تعداد نتایج: 414  

Journal: :ACS nano 2016
Loai K E A Abdelmohsen Marlies Nijemeisland Gajanan M Pawar Geert-Jan A Janssen Roeland J M Nolte Jan C M van Hest Daniela A Wilson

Self-powered artificial nanomotors are currently attracting increased interest as mimics of biological motors but also as potential components of nanomachinery, robotics, and sensing devices. We have recently described the controlled shape transformation of polymersomes into bowl-shaped stomatocytes and the assembly of platinum-driven nanomotors. However, the platinum encapsulation inside the s...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2009
Younghoon Kim Manorama Tewari J David Pajerowski Shenshen Cai Shamik Sen Jason H Williams Shashank R Sirsi Gordon J Lutz Dennis E Discher

siRNA and antisense oligonucleotides, AON, have similar size and negative charge and are often packaged for in vitro delivery with cationic lipids or polymers-but exposed positive charge is problematic in vivo. Here we demonstrate loading and functional delivery of RNAi and AON with non-ionic, nano-transforming polymersomes. These degradable carriers are taken up passively by cultured cells aft...

Journal: :Soft matter 2017
Nestor Lopez Mora Yue Gao M Gertrude Gutierrez Justin Peruzzi Ivan Bakker Ruud J R W Peters Bianka Siewert Sylvestre Bonnet Roxanne E Kieltyka Jan C M van Hest Noah Malmstadt Alexander Kros

Giant Unilamellar Vesicles (GUVs) prepared from phospholipids are becoming popular membrane model systems for use in biophysical studies. The quality, size and yield of GUVs depend on the preparation method used to obtain them. In this study, hydrogels consisting of dextran polymers crosslinked by poly(ethylene glycol) (DexPEG) were used as hydrophilic frameworks for the preparation of vesicle ...

2016
Wenda Wang Hao Qi Tian Zhou Shan Mei Lin Han Takeshi Higuchi Hiroshi Jinnai Christopher Y Li

Lipids and amphiphilic block copolymers spontaneously self-assemble in water to form a plethora of micelles and vesicles. They are typically fluidic in nature and often mechanically weak for applications such as drug delivery and gene therapeutics. Mechanical properties of polymeric materials could be improved by forming crystalline structures. However, most of the self-assembled micelles and v...

Journal: :Proceedings of the National Academy of Sciences 2006

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