Please cite this article in press as: Yokoya Diagnosis of Solid Tumors, Journal of Exper Polymeric micelles are assemblies of synthetic polymers and have been studied and developed as drug carriers for targeting solid tumors. Physicochemical characters and medical advantages of the polymeric micelle carrier systems are summarized, followed by an explanation of their recent application for contr...

Electro-optic (EO) polymeric Mach-Zehnder (MZ) modulators with photo-bleaching (PB) induced waveguides and dual driving electrodes operating at 1.55 mm wavelength have been demonstrated. The halfwave voltage of the integrated polymeric modulator was 4.5 V in a push–pull configuration with a 1.5 cm interaction length. The extinction ratio was greater than 20 dB, and the fibre-to-fibre insertion ...

A “water free,” proton conducting membrane for use in a fuel cell is fabricated as a highly conducting sheet of converted solid state organic amine salt, such as converted acid salt of triethylenediamine with two quaternized tertiary nitrogen atoms, combined with a nanoparticulate oxide and a stable binder combined with the converted solid state organic amine salt to form a polymeric electrolyt...

Different kinds of additive and reactive flame retardants containing phosphorus are increasingly successful as halogen-free alternatives for various polymeric materials and applications. Phosphorus can act in the condensed phase by enhancing charring, yielding intumescence, or through inorganic glass formation; and in the gas phase through flame inhibition. Occurrence and efficiency depend, not...

In the crystal of the title polymeric compound, [HgI(2)(C(4)H(5)N(3))](n), the Hg(II) cation is located on a twofold rotation axis and is coordinated by two I(-) anions and two 2-amino-pyrazine ligands in a distorted HgI(2)N(2) tetra-hedral geometry. In the crystal, the 2-amino-pyrazine ligand is equally disordered over two positions about an inversion center, and bridges the Hg(II) cations wit...

In the title polymeric Cu(I) compound, [Cu(2)Br(2)(C(12)H(10)N(2))](n), the Cu cation is coordinated by an N atom from the 1,2-bis-(4-pyrid-yl)ethene ligand and three Br(-) anions in a distorted tetra-hedral CuBr(3)N coordination geometry. Each Br(-) anion bridges three Cu cations related by inversion centers, forming a stair-like polymeric chain along the a axis, and the terminal N atoms of th...

Polymeric multilayer capsules have emerged as a novel drug delivery platform. These capsules are fabricated through layer-by-layer sequential deposition of polymers onto a sacrificial core template followed by the decomposition of this core yielding hollow capsules. The resulting nanometer thin membrane is permselective, allowing diffusion of water and ions but excluding larger molecules. Moreo...

Amphiphilic surfactants, molecules with chemical moieties that interact differently with the solvating medium, are important for technological applications and ubiquitous in biology. Understanding how to control surfactant properties is, therefore, of wide-ranging importance. Using a combination of light scattering experiments and field theory, we demonstrate that the behavior of polymeric surf...

Separation of compounds out of complex mixtures is a key issue that has been solved for small molecules by chromatography. However, general methods for the separation of large bio-particles, such as cells, are still challenging. We demonstrate integration of imprinted polymeric films (IPF) into a microfluidic chip, which preferentially capture cells matching an imprint template, and separate st...

We have studied the effects of brefeldin A (BFA) on the polarized delivery of the polymeric immunoglobulin receptor to the basolateral surface of MDCK cells. Unlike the delivery of several other basolateral membrane and secretory proteins, the delivery of the polymeric immunoglobulin receptor from the trans-Golgi network to the cell surface was inhibited by BFA. The effect of BFA treatment was ...