نتایج جستجو برای: polycystic ovary syndrome premenopausal breast cancer endocrine disorder

تعداد نتایج: 2118010  

Journal: :Journal of neuroendocrinology 2008
E Stener-Victorin E Jedel L Mannerås

This review describes the aetiology and pathogenesis of polycystic ovary syndrome (PCOS) and evaluates the use of acupuncture to prevent and reduce symptoms related with PCOS. PCOS is the most common female endocrine disorder and it is strongly associated with hyperandrogenism, ovulatory dysfunction and obesity. PCOS increases the risk for metabolic disturbances such as hyperinsulinaemia and in...

Journal: :journal of reproduction and infertility 0

background: polycystic ovary syndrome (pcos) is a complex, multifaceted, heterogeneous disorder, affecting 4%-18% of reproductive-aged women and it is associated with reproductive, metabolic and psychological dysfunctions. pcos affects quality of life and can worsen anxiety and depression either due to the features of pcos or due to the diagnosis of a chronic disease. methods: in this descripti...

Journal: :Hormone molecular biology and clinical investigation 2010
Abdulmaged M Traish Katharina Fetten Martin Miner Michael L Hansen Andre Guay

The objective of this review was to examine data from preclinical, clinical and epidemiological studies to evaluate if testosterone (T) poses increased risk of breast cancer in women. Appraisal of the existing literature produced several lines of evidence arguing against increased breast cancer risk with T. These include: (i) Data from breast tumor cell lines treated with androgens did not corr...

Journal: :Middle East Fertility Society Journal 2023

Abstract Background Polycystic ovary syndrome (PCOS) is the most typical endocrine disorder affecting women worldwide. Although etiology of PCOS not fully understood, genetic factors are believed to play an essential role in its pathogenesis. Hence, this paper presents a review outcome functional enrichment analysis pathways associated with phenotypes for identification potential molecular targ...

2015
Claudia Agnoli Sara Grioni Sabina Sieri Carlotta Sacerdote Fulvio Ricceri Rosario Tumino Graziella Frasca Valeria Pala Amalia Mattiello Paolo Chiodini Licia Iacoviello Amalia De Curtis Salvatore Panico Vittorio Krogh Eugenio Paci

BACKGROUND Metabolic syndrome (defined as at least three among abdominal obesity, high blood triglycerides, low high-density lipoprotein cholesterol, high blood glucose, and high blood pressure) is emerging as a risk factor for breast cancer; however few studies - most confined to postmenopausal women - have investigated associations between breast cancer risk and metabolic syndrome. The purpos...

Journal: :Cancer treatment reviews 2016
Lucia Del Mastro Giovanni Rossi Matteo Lambertini Francesca Poggio Paolo Pronzato

Luteinising hormone releasing hormone agonists (LH-RHa) are effective in the treatment of advanced endocrine-sensitive breast cancer in premenopausal patients, but their role in the adjuvant setting has remained controversial for a long time. Tamoxifen for 5 years has been traditionally considered the standard endocrine therapy for premenopausal patients and this is still valid for many patient...

Journal: :Cells 2023

Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder with disrupted uterus structure and function. A positive effect of vitamin D3 (VD3) in female reproduction was observed. Chemerin (RARRES2) adiponectin (ADIPOQ) are the main adipokines whose levels altered PCOS patients. Therefore, aim this study to investigate impact VD3 supplementation on RARRES2 ADIPOQ rats. Methods: We an...

Journal: :Human reproduction 2002
Adam Balen Kathy Michelmore

Polycystic ovary syndrome (PCOS) is a true syndrome, being a heterogeneous collection of signs and symptoms that gathered together form a spectrum of a disorder with a mild presentation in some, whilst in others there is a severe disturbance of reproductive, endocrine and metabolic function. There has been much debate about phenotype and, more recently, genotype. There has also been scepticism ...

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