POLYCYSTIC OVARY SYNDROME, A COMPLEX ENTITY INVOLVING REPRODUCTIVE AND METABOLIC IMPAIRMENTS (Abstract): A SYSTEMATIC REVIEW (Abstract): We attempt to synthesize main data in what concerns pathogenesis, signs and symptoms, diagnosis and management of polycystic ovary syndrome PCOS. The issue was the systematization of main data regarding different features of PCOS and stressing its peculiar ass...

In addition to its effects on reproductive health, it is now well recognized that polycystic ovary syndrome (PCOS) is a metabolic disorder, characterized by decreased insulin sensitivity which leads to an excess lifetime risk of type 2 diabetes and cardiovascular disease. PCOS patients are often obese, hypertensive, dyslipidemic and insulin resistant; they have obstructive sleep apnea and have ...

Women with polycystic ovarian syndrome have chronic anovulation and androgen excess not attributable to another cause. This condition occurs in approximately 4% of women. The fundamental pathophysiologic defect is unknown, but important characteristics include insulin resistance, hyperandrogenism, and altered gonadotropin dynamics. Inadequate follicle-stimulating hormone is hypothesized to be a...

PCOS is characterised by a varied and often complex array of metabolic and endocrine abnormalities. The syndrome was originally described by Stein and Leventhal in 1935, as a triad consisting of amennorhoea, hirsutism and obesity, in women who had multiple cysts on their ovaries.1 Over the last decade or so, the understanding of this syndrome has changed and the emphasis is often on the long-te...

Objective: To study the effects of exenatide combined with clomifene citrate on the levels of Angiotensin (Ang) II/Angiotensin-(1-7) and insulin resistance in patients with polycystic ovary syndrome (PCOS). Methods: A total of 78 patients with PCOS who were treated in our department from January 2015 to January 2017 were included in the study. Patients were randomly divided into observation gro...

History of Polycystic Ovary Syndrome Although the first description of polycystic ovary syndrome (PCOS) is generally credited to Stein and Leventhal in 1935, it may have been observed as early as 1721, when the Italian scientist Antonio Vallisneri observed “young married peasant women, moderately obese and infertile, with two larger than normal ovaries, bumpy and shiny, whitish, just like pigeo...

History of Polycystic Ovary Syndrome Although the first description of polycystic ovary syndrome (PCOS) is generally credited to Stein and Leventhal in 1935, it may have been observed as early as 1721, when the Italian scientist Antonio Vallisneri observed “young married peasant women, moderately obese and infertile, with two larger than normal ovaries, bumpy and shiny, whitish, just like pigeo...

Wedge resection of the ovary was carried out in 45 anovulatory women to study the correlation between the degree of disturbance of ovulation and the histopathological findings. Polycystic ovary was always found in patients with anovulatory cycles. The ovaries in grade 1 amenorrhea showing withdrawal bleeding in response to gestagen alone belonged to the nonspecific type, polycystic type and scl...

Dear Editor: The recent report on serum anti-Müllerian hormone (AMH) levels and phenotypes of polycystic ovary syndrome is very interesting [1]. Hwang et al. [1] concluded that “high serum AMH levels cannot predict the phenotype of polycystic ovary syndrome (PCOS) and metabolic disturbances in PCOS patients in the non-obese group”. Notably, the results from this work are totally different from ...

In a study of 102 women (Arabs and Asians) with hirsutism, polycystic ovary syndrome was diagnosed in 93 patients (91%) including 26 cases with hirsutism and regular menstrual periods. In more than half of the cases the diagnosis was made on the basis of transabdominal ultrasonography, which was the single test with the highest yield. Luteinising hormone hyperresponsiveness to gonadotropin-rele...