This volume contains the twenty-six papers and the discussions which followed them as well as the twenty exhibits presented at the Third International Poliomyelitis Conference in Rome in 1954. The field was covered under the headings: Social Aspects, Acute Medical Care, Infection and Immunity, Developments in Tissue Culture, Orthopedics, Physical Medicine and Rehabilitation, and, finally, Trend...

Post-polio syndrome is a condition characterized by increased muscle weakness, atrophy, fatigue and pain developing several years after the acute polio event. We describe a 52-year-old patient who experienced post-polio syndrome; he had contracted acute paralytic poliomyelitis at 12 months of age, shortly after the third dose of Salk polio vaccine.

When included in a sequential polio vaccination schedule, inactivated polio vaccine (IPV) reduces the risk for vaccine-associated paralytic poliomyelitis (VAPP), a rare adverse event associated with receipt of oral poliovirus vaccine (OPV). During January 2014, the World Health Organization (WHO) recommended introduction of at least 1 IPV dose into routine immunization schedules in OPV-using co...

The diagnosis of paralytic poliomyelitis is now rarely considered in cases ofacute lower motor neurone weakness in patients resident in Britain. Paralytic poliomyelitis still occurs,' however, and we report two cases, one of which would not have occurred had the present immunisation procedures been followed. The occurrence of the other case suggests that immunisation procedures should be modifi...

INTRODUCTION With the high proportion of refugee population throughout Lebanon and continuous population movement, it is sensible to believe that, in particular vulnerable areas, vaccination coverage may not be at an optimal level. Therefore, we assessed the vaccination coverage in children under 5 in a district of the Akkar governorate before and after a vaccination campaign. During the vaccin...

1958, three years before the nationwide implementation of governmentally organised mass vaccination campaign against poliomyelitis using Sabin’s vaccine, Austrian federal province Vorarlberg was seized by an outbreak infantile paralysis. Due to enormous number infections and high mortality rate, this epidemic most severe in history Vorarlberg. In spring regional authorities provinces started ...

This report presents the recommendations of a WHO Expert Committee commissioned to coordinate activities leading to the adoption of international recommendations for the production and quality control of vaccines and other biologicals and the establishment of international biological reference materials. The report starts with a discussion of general issues brought to the attention of the Commi...

The introduction of combination vaccines plays a significant role in increasing vaccine acceptance and widening vaccine coverage. Primary vaccination against diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenza type b (Hib) diseases has been implemented in Vietnam. In this study we evaluated the safety and reactogenicity of combined diphtheria-tetanus-pertussis-inactivated po...